1,2,4-triazole is an important intermediate for the synthesis of pesticide fungicides, plant growth regulators, Paclobutrazol, diniconazole, Triadimefon, Triadimefon and so on. It can also be used as intermediates of a variety of pesticides, medicines and dyes. With the expansion of its application scope, its demand is increasing. 1,2,4-triazoles, as a valuable five membered heterocyclic framework, are widely used in many functional molecules, such as organic catalysis, materials science and so on. In addition, 1,2,4-triazole skeleton also appears in many bioactive molecules, which has important applications in pharmaceutical industry and pesticide.