Purpose: β- Lactamase inhibitor has strong irreversible inhibitory effect on penicillinase and cephalosporinase. Its antibacterial activity is very weak, so it is rarely used alone and often combined with others β- The combination of lactam antibiotics has obvious synergistic effect and is effective for most drug-resistant bacteria. Sulperzon, a compound preparation prepared with cefoperazone, was used to treat the infection of drug-resistant bacteria; And ampicillin to form a composite preparation.
Properties
Summary
Sulbactam acid is β- Lactamase inhibitors have strong and irreversible inhibitory effects on penicillinase and cephalosporinase. Its antibacterial activity is very weak, so it is rarely used alone, and often combined with other antibiotics β- The combination of lactam antibiotics has obvious synergistic effect on most drug-resistant bacteria. For example, sulbactam acid combined with cefoperazone is used to treat drug-resistant bacterial infections, and ampicillin combined with sulbactam acid combined with cefoperazone is used to treat drug-resistant bacterial infections.For synthesis of sulbactam sodium
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