An amino acid derivative obtained from L-alanine under the protection of Fmoc. It is reported that it can be used to prepare an aromatic heterocyclic derivative (S) - 5 - (1-aminoethyl) - 2 - (3 - (cyclopropylmethoxy) - 4-methoxyphenyl) - N - (2,4-difluorobenzyl) thiazole-4-formamide hydrochloride. The pharmaceutical composition containing the compound has a good affinity for PDE4, especially for chronic respiratory obstruction.
Manufacturing
