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Product introduction:
This product is a strong alkaline low molecular weight protein, which is a sulfate of alkaline protein extracted from fresh mature sperm of suitable male fish. In modern pharmacology, this product is classified as anti heparin drugs.
Appearance: white or almost white powder, slightly soluble in water, insoluble in ethanol and ether. The aqueous solution shows an acidic reaction to litmus test paper.
Function and use:
This product has strong alkaline groups in its molecules and can combine with strong acidic heparin in vivo to lose its anticoagulant activity. It is a heparin antagonist. It is mainly applicable to: ① bleeding caused by excessive dosage of heparin (1mg of fish chemical Book protamine sulfate can neutralize 1mg of heparin). ② Some diseases have increased hemorrhagic heparin like substances. ③ Bleeding from other causes, such as menorrhagia, postpartum hemorrhage, bleeding tendency after radiotherapy, etc.
Matters needing attention:
High concentration rapid injection can produce symptoms such as hypotension, slow heart beat and dyspnea, so slow intravenous injection is appropriate. Excessive intravenous injection can lead to hyperfibrinolysis, anticoagulant effect and bleeding. Attention should be paid to controlling the dosage. Syringes can be cleaned or disinfected, but do not come into contact with alkaline substances.
Manufacturing
