Rufloxacin hydrochloride

Introduction: Rufloxacin Hydrochloride is a new generation of fluoroquinolones with long half-life and broad spectrum. The bactericidal mechanism is to inhibit bacterial helicase, which is necessary for bacterial DNA de helix. Inhibition results in the accumulation of DNA in the de helix state, resulting in the inability of bacteria to survive. Rufloxacin has strong antibacterial effect on aerobic Gram-positive and Gram-negative bacteria, especially those causing urethral and respiratory tract infection.

CAS: 106017-08-7

Molecular formula: C17H19ClFN3O3S

Molecular weight: 399.87

Structural type:

Purpose: Rufloxacin Hydrochloride is a tricyclic quinolone drug, which has good antibacterial effect on Gram-negative bacteria, including Escherichia coli, Salmonella typhi, Shigella, Haemophilus influenzae and Neisseria gonorrhoeae. It also has certain antibacterial effect on Gram-positive cocci such as Staphylococcus and Streptococcus haemolyticus, Clinically, it is used for respiratory tract infection and urinary tract infection caused by sensitive bacteria.