Valine is one of twenty protein amino acids. From a nutritional point of view, valine is also an essential amino acid. Its English name valine is named after valerian, and its Chinese name is also called valine. Its codons are guu, Gua, GUC and GUG. It is a nonpolar amino acid. In sickle cell disease, valine in hemoglobin replaces the hydrophilic amino acid glutamate: because valine is hydrophobic, hemoglobin cannot fold correctly. Valine is completely electrically neutral. When its side chain is also neutral, and the charge generated by its amino and carboxyl groups is just balanced, this molecule is called zwitterion. Food sources rich in valine include white cheese, fish, poultry, cattle, peanuts, sesame seeds and shore beans.It is used in medicine as one of the components of amino acid infusion, and can also be used as a nutritional supplement
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