2-Amino-5-guanidinovaleric acid monohydrochloride is an amino acid drug, which can participate in the ornithine cycle, promote the transformation of blood ammonia into non-toxic urea through the ornithine cycle, so as to reduce blood ammonia. However, if the liver function is poor, the enzyme activity of urea formation in the liver will decrease, so the effect of arginine on reducing blood ammonia is not ideal. It is suitable for liver coma patients who are not suitable for sodium ion infusion.