Hydroxypropyl methylcellulose (HMPC) CAS NO.: 9004-65-3
SHANDONG MEDICAL PRODUCTION LICENSE NO. F2014061
Packing specifications: 20 kg/bag 20 kg/bucket
Quality standard: CP2015, USP current edition
Main application:
The product is non-ionic cellulose ether, mainly used as filmogen and gels of thin film coating and emulgator, suspending agent and stabilizer of ointment. The concentration generally is 2%-10%. In tablet granulation, it is used as adhesive, with concentration generally of 2%-5%. Hydroxypropyl methylcellulose is widely used in oral and topical preparations, mainly used as adhesive of tablet, thin film coating material and framework material of sustained-release tablet; for low viscosity, it can be used as adhesive of wet granulation tablet and adhesive of dry granulation; and the hydroxypropyl methylcellulose with high viscosity can be used as retardant of framework of tablet and capsule, with the function of delaying drug release.
Indicator/model | USP/CP2910(60EH) | USP/CP2906(65EH) | USP/CP2208(70EH) | USP/CP1828(90EH) |
Methoxy group % | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 | 16.5-20.0 |
Hydroxypropoxy % | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 | 23.0-32.0 |
Residue on ignition | ≤1.5% | |||
Heavy metal | ≤0.002% | |||
PH | 5.0-8.0 | |||
Application | 2910(60EH) is suitable for adhesive of wet granulation, conventional thin film coating material and closed tablet core; 2208(70EH) is applied to matrix tablet of sustained-release preparations; 2906(65EH) is often used as thickening agent. |