2-(4-Bromomethyl)Phenylpropionic Acid

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CAS NO.： 111128-12-2

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Product Detail

Properties

2 - (4-Bromomethylphenyl) propionic acid

Chinese Name: 2-（4-溴甲基苯基）丙酸

Common Name: 2 - (4-bromomethyl) phenylpropionic acid

Chemical formula:C₁₀H₁₁BrO₂

Molecular weight: 243.10

CAS No.: 111128-12-2

Purpose: to synthesize the key intermediate of loxoprofen sodium.

Properties

2-[4-(Bromomethyl)phenyl]propanoic acid is a key pharmaceutical intermediate for the synthesis of loxoprofen from toluene by Friedel crafts, willgerodt Kindler hydrolysis "one pot method", monomethylation and bromination. Loxoprofen is a non steroidal anti-inflammatory drug. It is used for analgesia and anti-inflammatory after operation, trauma and tooth extraction.

CAS No.

111128-12-2

Formula

C10H11BrO2

Molecular Mass

243.09700

Exact Mass

241.99400

PSA

37.30000

Logp

2.76960