Methylcellulose (MC)

Methylcellulose (MC) CAS NO.: 9004-67-5

SHANDONG MEDICAL PRODUCTION LICENSE NO. F2014060

Packing specifications: 20 kg/bag

Quality standard: CP2015 USP current edition

Main application:

The product is usually used as adhesive, with good low or medium viscosity grade. It can be added in solution or powder to improve disintegration/ dissolution rate, and the general concentration is 1-20%; Select high viscosity grade for gels, thickening gel and cream; For tablet coating, it is used to wrap the core as isolation layer prior to sugar-coating; For disintegrant, select high viscosity grade, and use the expansive action after it contacts with disintegration medium, the general concentration is 2-10%. The product is also food additives, used in production of ice cream, colored particle, bread, etc.

Indicator/model	MC20	MC450	MC2500	MC4500
Viscosity (2% solution) mPa.s	16-24	330-630	1800-3500	3300-6300
Methoxy group, %	27.0-32.0	27.0-32.0	27.0-32.0	27.0-32.0
Loss on drying, %	≤5.0	≤5.0	≤5.0	≤5.0
Residue on ignition, %	≤1.0	≤1.0	≤1.0	≤1.0
PH	5.0-8.0	5.0-8.0	5.0-8.0	5.0-8.0
Heavy metal, %	≤0.002	≤0.002	≤0.002	≤0.002
Arsenic salt, %	≤0.0002	≤0.0002	≤0.0002	≤0.0002

Properties

Methylcellulose is widely used in construction industry, such as cement, mortar, joint desliming and so on. It is used as film-forming agent and adhesive in cosmetics, medicine and food industry. It is also used as sizing agent for textile printing and dyeing, synthetic resin dispersant, coating film-forming agent and thickener. Alkali cellulose is prepared from pulp, which reacts with methyl chloride or dimethyl sulfate in an autoclave, and then refined with warm water. Methylcellulose is generally considered safe, non-toxic, non allergenic and non irritating. In the pharmaceutical industry, methylcellulose with low or medium viscosity can be used as the adhesive of tablets and also for tablet coating. High viscosity methylcellulose can be used to modify disintegration or as skeleton material of sustained-release preparation. Methylcellulose with high degree of substitution and low viscosity can be used for aqueous coating, suspension aid, thickener, emulsion stabilizer and protective colloid. High degree of substitution and high viscosity methyl cellulose can be used in eye drops, and can also be used as matrix material for cream or gel.

CAS No.

9004-67-5

Formula

C20H38O11

Molecular Mass

658.72900

Exact Mass

658.34100

PSA

147.68000

Logp

-0.37790