Benzyl (3R,4S)-3-(2-Bromoacetyl)-4-Ethylpyrrolidine-1-Carboxylate

Home > API & Intermediate > Pharmaceutical Intermediates > Benzyl (3R,4S)-3-(2-Bromoacetyl)-4-Ethylpyrrolidine-1-Carboxylate Manufacturers > Benzyl (3R,4S)-3-(2-Bromoacetyl)-4-Ethylpyrrolidine-1-Carboxylate

CAS NO.： 1428243-26-8

FOB Price： NEGOTIABLE Get Latest Price

Specification： EP

Documentation： Get COA after inquiry

Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

Chemical name

English name： Benzyl (3R,4S)-3-(2-Bromoacetyl)-4-Ethylpyrrolidine-1-Carboxylate

CAS No.: 乌帕替尼中间体

Physicochemical properties：

Molecular formula: C16H20BrNO3

Structural type:

Molecular weight: 354.239

Boiling point: 453.1±45.0 °C(Predicted)

Density： 1.361±0.06 g/cm3(Predicted)

Purpose: Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate is a key intermediate of upatinib. At the beginning of 2018, the oral Jak1 selective inhibitor upadacitinib (abt-494), developed by abbvie in the United States once every day for the treatment of adult moderate and severe atopic dermatitis, was recognized as a breakthrough therapy by FDA.

Properties

Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate is a key intermediate of upatinib. At the beginning of 2018, the oral Jak1 selective inhibitor upadacitinib (abt-494), developed by abbvie in the United States once every day for the treatment of adult moderate and severe atopic dermatitis, was recognized as a breakthrough therapy by FDA.

CAS No.

1428243-26-8

Formula

C16H20BrNO3

Molecular Mass

354.23900

Exact Mass

353.06300

PSA

46.61000

Logp

3.18310

IUPAC

benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate

Matter Classification

organic

Category

Density

1.361±0.06 g/cm3(Predicted)

Boiling Point

453.1±45.0 °C(Predicted)

HS Code

29339900

Send your message to this supplier

To：

Kaifeng Mingren Pharmaceutical Co.,LTD.

Not exactly what you want? One request, multiple quotations Get Quotations Now >>

Supplier's main products

b

Send Email