(4R,6R)-Tert-Butyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate

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CAS NO.： 125971-94-0

FOB Price： NEGOTIABLE Get Latest Price

Specification： ≥98.5%

Documentation： Get COA after inquiry

Lead Time： In Stock

Max Capacity： -

Pallets Packing	20'FCL		40'FCL
Pallets Packing	With	Without	With	Without
25KG/Fibre Drum	--	20 MT	--	--

Product Detail

Properties

(4R,6R)-Tert-Butyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate

(4R,6R)-Tert-Butyl-6-Cyanomethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate is used as an intermediate of atorvastatin. Atorvastatin is a selective competitive HMG CoA reductase inhibitor, which can significantly reduce LDL CH and triglyceride, but does not cause the redistribution of triglyceride, but constantly reduces TG in all lipoprotein components. It is suitable for the patients with primary hypercholesterolemia, heterozygous familial hypercholesterolemia or mixed hyperlipidemia, whose diet control can not effectively reduce the average total cholesterol, low density lipoprotein cholesterol and triglyceride. It is also suitable for patients with heterozygous familial hypercholesterolemia who have diet control at the same time.

Product Appearance：

Product Type	Atorvastatin Intermediate
Product Name	ATS-8
CAS No	125971-94-0
Molecular formula	C₁₁H₂₃O₄N
Structural formula
Quality Index	Quality Standard: Enterprise Standard Appearance: white to off-white crystalline powder Content: ≥98.5% Moisture: <0.5% Melting point: 64-70 ° C Packing: cardboard drum 25kg/drum
Uses	Pharmaceutical intermediate, main raw material for atorvastatin clacium

Properties

Tert-butyl 2-[(4R,6R)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate is used as an intermediate of atorvastatin. Atorvastatin is a selective competitive HMG CoA reductase inhibitor, which can significantly reduce LDL CH and triglyceride, but does not cause the redistribution of triglyceride, but constantly reduces TG in all lipoprotein components. It is suitable for the patients with primary hypercholesterolemia, heterozygous familial hypercholesterolemia or mixed hyperlipidemia, whose diet control can not effectively reduce the average total cholesterol, low density lipoprotein cholesterol and triglyceride. It is also suitable for patients with heterozygous familial hypercholesterolemia who have diet control at the same time.

CAS No.

125971-94-0

Formula

C14H23NO4

Molecular Mass

269.33700

Exact Mass

269.16300

PSA

68.55000

Logp

2.54208