Fosfomycin calcium is mainly used for colibacillosis, salmonellosis, Klebsiella disease, head swelling syndrome, Staphylococcus and Streptococcosis, omphalitis, osteomyelitis, encephalitis of poultry and pigs, as well as the infection caused by Pasteurella, Vibrio, Streptococcus and other gram-negative bacteria in fish and shrimp.