Synonymous: | Diovan;Tareg |
CAS: | 137862-53-4 |
Molecular Formula: | C24H29N5O3 |
Molecular Weight: | 435.519 |
Appearance | White crystal or white, off white powder |
Storage | Keep in a cool place away from light |
Category | Drugs for treating hypertension |
Valsartan is an angiotensin II receptor antagonist antihypertensive drug. It can block the type I (AT1) receptor of angiotensin II, increase the plasma level of angiotensin II, stimulate the unsealed AT2 receptor, and counter the AT1 receptor, so as to expand blood vessels and reduce blood pressure. In the United States, valsartan is a drug used to treat hypertension, congestive heart failure and post myocardial infarction.
Antihypertensive drugs. Valsartan is an angiotensin Ⅱ (Ang Ⅱ) receptor antagonist, which can selectively block the binding of Ang Ⅱ to AT1 receptor (its specific antagonistic effect against AT1 receptor is about 20000 times greater than AT2), so as to inhibit vasoconstriction and aldosterone release and produce antihypertensive effect.
Anti hypertension, mild to moderate essential hypertension, especially for secondary hypertension caused by renal damage.
It is forbidden for those who are allergic to the drug and pregnant and lactating women.
Usage and dosage:
Due to different dosage forms and specifications, please read the drug instructions carefully or follow the doctor's advice.
Headache, dizziness, cough, diarrhea, nausea, abdominal pain, fatigue, etc. Neutropenia can also occur. Occasionally, the indexes of liver function increased.
(1) Angioneuroedema (2) aortic valve or left atrioventricular valve stenosis (3) cholestasis or bile duct obstruction (4) lactation (5) coronary artery disease (6) elderly (7) liver dysfunction (8) hypertrophic cardiomyopathy (9) hyponatremia or reduced blood volume, such as high-dose diuretics (10) unilateral or bilateral renal artery stenosis (11) Surgical patients requiring general anesthesia