N-[5-(Diphenylphosphorylmethyl)-4-(4-Fluorophenyl)-6-Propan-2-Ylpyrimidin-2-Yl]-N-Methylmethanesulfonamide

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CAS NO.： 289042-10-0

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Specification： 99%

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Lead Time： 14-30 days

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Packing： 25KG/Fibre Drum

Product Detail

Properties

Intermediate of Rosuvastatin: Z-9

Chemical name: 4-(4-Fluorophenyl)-5-(diphenylphosphinyl)methyl-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine

CAS：289042-10-0

Structural formula:

Molecular formula: C₂₈H₂₉FN₃O₃PS

Molecular weight: 537.58

Properties

This product is the intermediate of rosuvastatin calcium. Rosuvastatin calcium is a selective 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. By inhibiting HMG CoA reductase, rosuvastatin calcium can reduce the synthesis and storage of cholesterol in hepatocytes, thereby reducing the levels of total cholesterol and low density lipoprotein cholesterol in blood.

CAS No.

289042-10-0

Formula

C28H29FN3O3PS

Molecular Mass

537.58500

Exact Mass

537.16500

PSA

98.42000

Logp

6.39680