Application: methyl 2-methoxy-5-sulfonamide benzoate is an important intermediate of antipsychotics sulpiride and L-sulpiride. At present, salicylic acid is used to synthesize this product through methylation, chlorosulfonation, amination and esterification at home and abroad. Its process route is long and the amount of three wastes produced in each step is large, In particular, high chemical oxygen demand (COD), high salt, high ammonia nitrogen and mixed wastewater are difficult to treat and the treatment cost is very high, which seriously restricts the large-scale industrial production of the product.
Properties
Summary
Methyl 2-methoxy-5-sulfonamide benzoate is an important intermediate of antipsychotics sulpiride and L-sulpiride. At present, salicylic acid is synthesized by methylation, chlorosulfonation, amination and esterification at home and abroad. The process route is long, and the three wastes produced in each step are large, especially high chemical oxygen demand (COD), high salt, high ammonia nitrogen and mixed wastewater, The difficulty and high cost of treatment seriously restrict the large-scale industrial production of the product.