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Product Name:Daily Chemical Grade Hydroxypropyl Beta Cyclodextrin
CAS No.:128446-35-5
DMF No.:030168
Quality Standard:CP/USP/EP
Basic Information:
Product Name:Daily Chemical Grade Hydroxypropyl Beta CyclodextrinDextrin
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Molecular formula :C42H70-nO35(C3H7O)n
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Molecular weight:1134.98+58n
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Quality Standard:
Inspection standards | CP2020 | USP-NF2021 |
Test items | Index | Index |
Traits | This product is white or off-white amorphous or crystalline powder; odorless, slightly sweet taste; strong hygroscopicity.Very soluble in water, easily soluble in methanol or ethanol, almost insoluble in acetone or chloroform. | This product is white or off-white amorphous or crystalline powder; easily soluble in water and propylene glycol. |
Molar substitution | N/A | 0.4-1.5 |
Solution clarity and color | Should be clear and colorless | 1.0g/2ml aqueous solution is clear and transparent |
Identify | A purple ring should appear at the interface between the two liquids | The infrared spectrum shows the same absorption band (infrared) as the standard sample |
PH | PH5.0-7.5 | N/A |
Moisture | ≤6.0% | ≤10.0% |
Conductivity | N/A | ≤200μS/cm |
Propylene oxide | N/A | ≤1ppm |
1.2-Propanediol | ≤0.5% | ≤2.5% |
Other individual impurities | N/A | ≤0.25% |
Other total impurities | N/A | ≤1.0% |
Betacyclodextrin | ≤0.5% | ≤1.5% |
Residue on ignition | ≤0.2% | N/A |
Heavy metal | Less than 10 parts per million | N/A |
Chloride | ≤0.05% | N/A |
Hydroxypropoxy content | 19.6%～26.3% | N/A |
Total aerobic bacteria (cfu/g) | N/A | ≤1000cfu/g |
Total mold and yeast (cfu/g) | N/A | ≤100cfu/g |
Total number of pathogenic bacteria (cfu/g) | N/A | Not checked out |
Bacterial endotoxin | N/A | According to formulation needs |
Product performance:
The introduction of hydroxypropyl breaks the intramolecular cyclic hydrogen bond of beta-cyclodextrin, and overcomes the beta-cyclodextrin while maintaining the cyclodextrin cavity. The main disadvantage of the poor water solubility of dextrin.Hydroxypropyl betacyclodextrin is an ideal solubilizer and excipient.
Scope of application:
Daily chemical grade hydroxypropyl beta cyclodextrin can be used in cosmetic products.
Packaging andstorage:
Packaging:In line with drug packaging
packaging specifications:0.5kg bag, 1kg/bag, 2kg/bag, 10kg/bag/drum, 20kg/bag/ Barrel
storage: shading, airtight storage
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