N,O-bis(trimethylsilyl)trifluoroacetamide is an important pharmaceutical intermediate, which can reduce the polarity of hydroxyl compounds, increase their volatility and make samples more suitable for GC analysis. It is mainly used as neutral silylation reagent in the silylation protection of amino acids, amino acids, phenols, carboxylic acids and enols. As a mild neutral silylation reagent, it not only has high activity and selectivity, but also has the advantages of high yield and simple post-treatment.
Manufacturing
