Povidone Iodine

Product overview

Povidone iodine is a complex of povidone K30 and iodine. It has a strong killing effect on bacteria, viruses, fungi, molds and spores. Stable, non irritating, completely water-soluble.

Product attributes

Pharmacopoeia Name: povidone iodine, povidone iodine (USP), povidone iodinated (EP)

Chemical name: complex of polyvinylpyrrolidone and iodine

INCI/CTFA：PVP-Iodine

CAS No.: 25655-41-8

Action mechanism: PVP is a hydrophilic polymer and has no antibacterial effect. However, due to its affinity for cell membrane, it can directly introduce iodine to the cell surface of bacteria, which is of great significance to improve the antibacterial activity of iodine. The attack target of iodine is bacterial cytoplasm and cytoplasmic membrane, which can kill bacteria immediately in a few seconds. When the molecules necessary for biological survival such as hydrophobic compounds, peptides, proteins, lipids and cytosine come into contact with PVP-I, they are immediately oxidized or iodized by iodine to lose their activity and achieve long-term bactericidal effect.

quality standard

Packaging and storage: 25kg / cardboard barrel, shaded and sealed, stored in a cool and dry place.

Application performance: Povidone iodine has a broad spectrum of microbial killing or inhibition, and can kill a variety of gram-positive and negative bacteria, tetracocci, Candida albicans, Bacillus subtilis, spores, fungi, Escherichia coli, dysentery bacilli, proteus, Citrobacter, diphtheria like bacilli, foreskin bacilli, Pseudomonas aeruginosa, Neisseria gonorrhoeae, Pseudomonas aeruginosa, anthrax like bacilli Flagellates, chlamydia. It is mainly used for gynecological inflammation, sore skin inflammation, oral inflammation, oral ulcer, scald, various trauma, surgery, skin disinfection before injection and disinfection of medical instruments; In addition, it is also used for sterilization and disinfection of household tableware and utensils; It is the first choice of disinfectants for sterilization and animal disease prevention in food industry and breeding industry.

Povidone iodine solution has no pungent smell, no irritation and damage to skin mucosa and respiratory tract, no secondary pollution and no drug resistance. It is easy to dilute, easy to use and stable. It is the most advanced environmental protection disinfectant at present. It has a good effect in the treatment of human burn, frostbite, knife injury, abrasion, contusion and other general trauma, especially suitable for skin inflammation, ulceration and other diseases. Because of its small irritation, slight pain compared with iodine and alcohol, it is easy to be accepted by patients, and has a wide range of uses and accurate effect. It basically replaces skin and mucous membrane disinfectants such as alcohol, red mercury, iodine and purple potion. In addition, when povidone iodine is mixed into a solution, it is gradually dissolved in water to release free iodine for sterilization. Due to the slow release of iodine in surfactant, the sterilization effect is lasting, the irritation is low, and the coloring effect disappears, overcoming the shortcomings of easy sublimation, yellow staining and irritation of iodine tincture.

It has been included in the latest Pharmacopoeia such as Chinese Pharmacopoeia 2010, USP 36 and European Pharmacopoeia 7.0.