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N,N'-Dicyclohexylcarbodiimide
CAS NO.: 538-75-0
FOB Price: NEGOTIABLE Get Latest Price
Specification: 99.0%
Documentation: Get COA after inquiry
Lead Time: 14-30 days
Max Capacity: 600MT/Year
Pallets Packing 20'FCL 40'FCL
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25KG/Fibre Drum
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200KG/Plastic Drum
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20 MT
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Product Detail
Properties

N,N'-Dicyclohexylcarbodiimide

English Name: N,N'-Dicyclohexylcarbodiimide

CAS No.: 538-75-0

Molecular formula: C13H22N2

Molecular weight: 206.33

EINECS No.: 208-704-1

Melting point: 34-35 ° C (lit.)

Boiling point: 122-124 ° C6 # mm Hg (lit.)

Density: 1.247 g / ml at 25 ° C

Application: mainly used for condensation of amino acids in peptide synthesis. For example, in Fmoc solid phase synthesis, the carboxyl group of an amino acid forms an amide bond with the amino group of another amino acid. In order to make the carboxyl group more vulnerable to attack by nucleophiles, the negatively charged oxygen atom needs to be activated into a better leaving group, and DCC plays this role. The oxygen atom of carboxyl group on amino acid acts as nucleophilic reagent to attack the carbon atom in the middle of DCC molecule, which makes DCC combine with carboxyl group to form ester structure, which makes the nucleophilic attack of amino acid easy

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13YRS
Business Type:
Manufacturing
Country/Region:
Hubei, China
Contacts:
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Sales manager
Tel:
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