Basic Information of 2-Pyridinethanol / CAS 103-74-2

1. English Name: 2-(2-Hydroxyethyl)pyridine or 2-Hydroxyethyl Pyridine or 2-Pyridinethanol
2. CAS Number: 103-74-2
3. Molecular Formula: C7H9NO
4. Molecular Weight: 123.15
5. Appearance: Colorless to slightly yellow transparent liquid, miscible with ethanol, ether, and water, hygroscopic
6. Physical Properties: Boiling point around 114-116°C (at lower pressure), density 1.093 g/mL (at 25°C), flash point 92.78°C, refractive index 1.5368-1.537

Chemical Properties

1. Due to the presence of hydroxyl and pyridine rings, 2-(2-Hydroxyethyl)pyridine exhibits certain hydrophilicity and reactivity.
2. It can participate in various organic synthesis reactions, such as catalytic reactions and free-radical polymerization reactions.

Specifications of 2-Pyridinethanol / CAS 103-74-2

Production Method of 2-Pyridinethanol / CAS 103-74-2

1. 2-(2-Hydroxyethyl)pyridine can be synthesized through the addition reaction of 2-methylpyridine and formaldehyde. Under nitrogen protection, the mixture of formaldehyde and 2-methylpyridine is heated to a certain temperature, and then subjected to reduced pressure distillation to collect the specific fraction.

Primary Uses of 2-Pyridinethanol / CAS 103-74-2

1. Pharmaceutical Intermediate: As a key intermediate in drug synthesis, 2-Hydroxyethyl Pyridine is used to synthesize various biologically active drugs, such as antibiotics, antiviral drugs, and anticancer drugs.
2. Flame Retardant: With certain flame retardant properties, it can be used in the production of flame retardants for polymers and plastics, enhancing the fire resistance of materials.
3. Polymer Materials: In polymerization reactions, 2-Hydroxyethyl Pyridine serves as a chain transfer agent, regulating the molecular weight and molecular weight distribution of polymers, thereby affecting their properties and structures.
4. Electronic Materials: It can be a component of organic semiconductor materials, used in the preparation of electronic devices such as organic thin-film transistors (OFETs).
5. Other Applications: It is also applied in the pharmaceutical industry, engineering plastics, ion exchange resins, and chemical films.

Safety Precautions of 2-Pyridinethanol / CAS 103-74-2

1. When working with 2-(2-Hydroxyethyl)pyridine, follow laboratory safety procedures, wear appropriate protective equipment, and ensure adequate ventilation.
2. Avoid direct skin contact and inhalation of its vapors. In case of accidental contact, rinse immediately with water and seek medical attention.
3. Storage: 2-(2-Hydroxyethyl)Pyridine should be stored in a dry, ventilated, and cool warehouse. If the storage time is long, a polymerization inhibitor should be added, and attention should be paid to fire prevention. It is strictly prohibited to store it together with flammable materials and oxidants. This product has a shelf life of 6 months from the date of production.
4. Transportation: During the transportation of this product, please pay attention to sealing, keeping it cool, and preventing leakage.

Fuyang Xinyihua Pharmaceutical Technology Co.,Ltd. was established in May 2017 with a registered capital of 228.5 million yuan. The company is located in Taihe County Economic Development Zone, Fuyang City, the largest western medicine distribution center in China and a provincial-level chemical concentration zone. Mainly engaged in the research and development, production, and sales of specialty pharmaceutical intermediates and active pharmaceutical ingredients, while providing professional pharmaceutical CMO/CDMO services. The current phase of the factory has a pilot workshop, two large multifunctional production workshops, and multiple standardized production lines, which can meet different process conditions such as -100 ℃~200 ℃ and 200Pa~7MPa.

With high-quality technology and manufacturing capabilities, the company has established stable customer relationships with hundreds of well-known domestic pharmaceutical companies, accumulated over 60 potential projects, and applied for more than 40 patents.

Keywords Related to 2-Pyridinethanol / CAS 103-74-2

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