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▶ High-Quality: adopt biosynthetic process, which can be mass-produced, and the content can reach 99.0% Min.
▶ Strong Supply Capacity: 100kg to tonnage.
▶ Competitive Price: The price of PQQ-2Na is 5%~10% lower than that of our competitors.
Product Name: | Pyrroloquinoline Quinone Disodium Salt | CAS No.: | 122628-50-6 |
MF: | C14H4N2Na2O8 | Abbr: | PQQ.2Na; PQQ-2Na |
Other Names: | Methoxatin Disodium Salt; PQQ Disodium Salt; Pyrroloquinoline Quinone.2Na; Pyrroloquinoline Quinone Disodium Salt Powder; | Application: | Food; Health Care Products; Medicine; Cosmetics; |
Grade Standard: | Food Grade; Pharm Grade; Cosmetic Grade | Purity: | ≥99% |
Transport Package: | Bags/Cases/Drums | Shelf Life: | 24 Months |
Appearance: | The reddish-brown crystalline powder | Origin: | China |
Application: | Pyrroloquinoline Quinone Disodium Salt is an effective component of nutritional ingredients currently sold in the market. It has nerve growth factor-inducing activity, has certain effects on Parkinson's disease, and can prevent immune liver injury | ||
5 Metric Tons Per Year
Packaging Details: | 5 KG/Drum, with inner aluminum foil bag or according to customer requirements |
Port: | Shanghai Port, or other main ports in China |
Items | Specifications | Results |
Appearance | Reddish brown crystalline powder. | Conforms |
Identification | The retention time of the major peak of the sample solution corresponds to that of the standard solution. | Conforms |
Purity | ≥99.0% | 99.60% |
Water content(%) | ≤12.0 | 11.1 |
Heavy metals(in lead)/ppm | ≤10 | Conforms |
As/ppm | ≤1.0 | Conforms |
Microbial limits | Total Aerobic Microbial Count<1000 | Conforms |
Total Yeasts and Molds Count≤100 | Conforms | |
Enterobacteriaceae≤100 | Conforms | |
E.coli(Negative) | Conforms | |
Salmonella(Negative) | Conforms | |
Saureus(Negative) | Conforms |
Holypharm Biotech is a company that uses the latest biosynthetic technology to produce the latest international cosmetics raw materials, nutritional ingredients, and preparations. The company is co-founded by business elites and brilliant scientists with strong academic backgrounds. We use synthetic bio-engineering technologies to provide innovative manufacturing solutions.
Through systematic engineering at the level of molecular (DNA manipulation, direct evolution of enzymes, etc.), cellular and sub-cellular (metabolic network rewriting and compartmentalization), and culturing (fermentation optimization), we manage to commercialize our designed microbial cell factories for large-scale bio-manufacturing of various products.
Supported by our professional expert team and outstanding GMP system, Holypharm offers Contract Research and Manufacturing (CRAM) services for active pharmaceutical ingredients (APIs) from synthesis and fermentation that cover all therapeutic areas.
Two solutions for our CRAM Services:
1. Produce APIs according to the dossier provided by customers.
2. Develop and optimize the manufacturing process from lab to commercial when a customer has limited techniques on target products.
We here guarantee that any inquiries from our customers and all projects undertaken by Holypharm will be kept confidential or protected by nondisclosure agreements if it is necessary.
▶ We have our GMP standard plants in Jiangsu and Zhejiang provinces, and 68 researchers in the R&D center in Wuhan and Tianjin. Moreover, we also have a close relationship with labs from the top 10 Chinese research institutes.
▶ We have expanded our business worldwide covering the major pharmaceutical markets, especially US and EU where our representative offices are located. Attributing to the efforts of our regulatory affairs (RA) experts, we are participating in the registration of several promising APIs in the US and EU as well as cooperating with Novartis, CHEMO, and Merck.
▶ We hold the gold relationship with both domestic and foreign pharmaceutical manufacturers, we are adept in re-arranging and co-ordinating their supply and demand on formulations to build up an excellent pipeline system that will benefit all the worldwide healthcare welfare.
Pyrroloquinoline Quinone Disodium Salt has the same functions and applications as PQQ, but PQQ Disodium Salt is more stable in nature and is used more frequently in practical applications.
Pyrroloquinoline quinone (PQQ) is a nutrient element produced by gram-negative bacteria, which has extensive nutritional effects on microorganisms, animals and plants, and has antioxidant properties. Pyrroloquinoline quinone widely exists in prokaryotes, plants and mammals. It is not only the auxiliary group of many enzymes, but also plays the role of transferring electrons, protons and chemical groups in enzymatic reactions. It can also stimulate the growth of microorganisms, the germination of plant pollen, and promote the growth of plants.
The discovery of PQQ is an important event in the history of quinone enzyme research. It not only makes people know a new auxiliary base but also means a new branch of enzymology will emerge: quinones, namely, oxidoreductases with PQQ and other quinones as cofactors. Before PQQ was discovered, it was thought that oxidoreductase had only two kinds of cofactors: NAD/NADP and FAD/FMN.
Pyrroloquinoline quinone disodium salt (PQQ-2Na) is a sodium derivative of pyrroloquinoline quinone (PQQ).
Pyrroloquinoline quinone disodium salt powder is an effective component of healthcare products currently sold in the market. PQQ-2Na has nerve growth factor-inducing activity, has certain effects on Parkinson's disease, and can prevent immune liver injury
Dietary supplement: At present, the common PQQ supplement products in the market are also mainly aimed at brain health, sleep aid, energy supplement, oral beauty, pregnancy aid, etc. Pyrroloquinoline quinone disodium salt powder are often used together with various raw materials such as MNM, coenzyme Q10, ginkgo Biloba extract, PS, etc.
▶ Quality: master the chemical synthesis and fermentation methods, which can be mass-produced, and the content can reach 99.0% Min.
▶ Strong supply capacity: 100kg to tonnage.
▶ The low price: The price of PQQ-2Na is more favorable than that of our peers.
PQQ has a strong ability to remove peroxides, which can effectively remove HO • and O2 • -, as shown in:
Protect mitochondria from oxidative damage; Inhibition of lipid peroxides; To protect myocardial cells from ischemia-reperfusion injury; Protect the redox sites of oxidized NMDA receptor, thus promoting the recovery of spinal cord injury, preventing cerebral ischemia and hypoxia, and avoiding severe shock in animal models; At the same time, PQQ can also protect the heart from myocardial ischemia and myocardial infarction. These protective effects are attributed to the antioxidant capacity of PQQ.
As a necessary factor for human development, PQQ can stimulate the growth of human cells, especially activating human B cells and T cells to produce antibodies and improve human immune function. PQQ is by far the most powerful bioactive substance found by humans.
PQQ can protect the liver against alcohol and carbon tetrachloride-induced liver injury and TAA-induced liver fibrosis.
PQQ is a new water-soluble vitamin, which can promote the synthesis of nerve factors in the human body and recuperate various nervous system diseases.
PQQ is the cofactor of quinone protease and participates in the electron transmission of the respiratory chain. It can promote the absorption of amino acids through the role of glucose in the human body.
A small amount of PQQ can improve the metabolic capacity and growth function of biological tissues.
The special biological activity and physiological function of PQQ also show that it can repair nerve fibers, activate neurons, activate dormant nerve cells, effectively prevent Alzheimer's disease and improve memory. It can effectively improve intelligence.
The mainstream is the chemical synthesis method and biosynthesis method.
Holypharm Biotech uses the biosynthesis method more and more while producing by chemical synthesis method.
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We are a manufacturer that owns GMP factories both in Jiangsu and Zhejiang Province. They cover an area of about 2000 mu. You are warmly welcome to visit us!
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