L-ascorbic acid 2-phosphate is a long-acting vitamin C derivative C It can stimulate the expression and formation of collagen. L-ascorbic acid 2-phosphate can be used as a culture medium to supplement the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increased alkaline phosphatase (ALP) activity and runx2a expression in Hasc during osteoblast differentiation.