Pesticide Intermediates

Pyridine is a six membered heterocyclic compound containing one aza atom, that is, a compound formed by the substitution of one carbon in benzene molecule with nitrogen. It is similar to benzene in that it has the same electronic structure and still has aromaticity. Pyridine and its derivatives are more stable than benzene, and their reactivity is similar to nitrobenzene. Due to the electron absorption of nitrogen atoms in the ring, the electron density at positions 2, 4 and 6 is lower than that at positions 3 and 5. The typical aromatic electrophilic substitution reaction occurs at positions 3 and 5, but the reactivity is lower than that of benzene, so it is generally not easy to nitration, halogenation and sulfonation. In addition, these substitution reactions are carried out in acidic medium. Pyridine forms positively charged ions, which make electrophilic reagents inaccessible. The halogens of 2-or 4-halopyridines are active. Because of the low electron density at positions 2 and 6, nucleophilic substitution reactions can take place at these positions, such as reaction with sodium amino or potassium hydroxide, to give corresponding 2-aminopyridine or 2-hydroxypyridine. Pyridine can also be used as denaturant and dyeing aid in industry, as well as the starting material for synthesis of a series of products, including drugs, disinfectants, dyes, food seasonings, adhesives, explosives and so on. Pyridine is toxic, inhalation, ingestion or skin contact can lead to reduced male fertility, can also cause cancer.

5-Chloro-8-hydroxyquinoline is an anti-bacterial, anti fungal, anti-aging and anti tuberculosis drug.

Sodium formate is an organic sodium salt which is the monosodium salt of formic acid. It has a role as a buffer and an astringent. (1) It can be used to produce formic acid, oxalic acid and sodium hydrosulfite. (2) It can be used as a reagent, disinfectant and mordant for the determination of phosphorus and arsenic. (3) It is a precipitant of heavy metals. It can precipitate precious metals and form trivalent metal complex ions in solution. (4) It has buffering effect and can correct the pH value of strong mineral acid. (5) It can be used as reducing agent. (6) It can be used in medicine, printing and dyeing industry. Used for alkyd resin coatings, plasticizers, high explosives, acid resistant materials, aviation lubricants, adhesive additives.

4-Fluorophenol is an important pharmaceutical and pesticide intermediate. It is used in the pharmaceutical industry for the synthesis of insecticidal drugs, gastrointestinal drugs and antiviral drugs, in the agricultural field for the synthesis of herbicides, plant growth regulators and in environmental engineering for algae removal.

P-Fluorobenzaldehyde is an important fine chemical intermediate, which is used as the main raw material for the synthesis of various pesticides, medicines, surfactants, polymer monomers, and antifungal agents. For example, it is used in medicine to synthesize antihypertensive drugs, antipyretic analgesic anti-inflammatory drugs, anti-cancer drugs, muscle relaxants, in pesticides, it is used to synthesize cyfluthrin and cyfluthrin, and to synthesize intermediate metaphenoxy. Base p-fluorobenzaldehyde, and polymer monomer p-fluorostyrene, of which p-fluorostyrene can be widely used in the manufacture of recording materials, thermoplastic resin coatings, liquid crystal materials, etc.