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CAS:2022-85-7
Molecular Formula:C4H4FN3O
5-Fluorocytosine; 4-Amino-5-Fluoro-2(1H)-Pyrimidinone,5-Fluorocytosine,Flucytosine; 4-Amino-5-Fluoro-1,2-Dihydropyrimidin-2-One; 4-Amino-5-Fluoro-2(1H)-Pyrimidinone,Flucytosine; 4-Amino-5-Fluoro-2-Pyrimidone; Fluocytosine; Ancotil; 5-Fluorocytosin; Fluorcytosine; 6-Amino-5-Fluoro-1H-Pyrimidin-2-One; Flucytosin; 5-Fluorocystosine; 4-Amino-5-Fluoro-2-Hydroxypyrimidine; 4-Amino-5-Fluoro-2(1H)-Pyrimidinone; Ancobon; Fluorocytosine
Brief Introduction
5-fluorocytosine (5-FC), also known as 5-fluorocytosine, 5-fluorocytidine, anjezhi, and anlapen, is a white or quasi white crystalline powder. The inhibitory effect of 5-fluorocytosine on fungi is due to its entering into the cells of sensitive fungi, and under the action of cytosine deaminase, 5-fluorouracil, an anti metabolite, is formed. The latter is converted to 5-fluorouracil-2-deoxyriboside, which inhibits thymidine synthase, blocks the conversion of 5-fluorouracil-2-deoxyriboside to thymidine, and affects DNA synthesis. It has a good inhibitory effect on Candida, Cryptococcus and hyphomycetes, and also has an effect on some Aspergillus, as well as mycospores and bottle fungi which cause skin fungal diseases.
CAS:209995-38-0
Molecular Formula:C8H5F3O2
(2,4,5-Trifluoro-Phenyl)-Acetic Acid; 2,4,5-Difluorophenylacetic Acid; 2-(2,4,5-Trifluorophenyl)Acetic Acid; 2,4,5-Triflurophenyl Acetic Acid; 2,4,5-Trifiuorophenylacetic Acid; 2,3-Dihydro-2-Oxobenzimidazole-5-Carboxylic Acid; Trifluorophenylacetic Acid; 2-(3,4-Difluorophenyl)-2-Fluoroacetic Acid; Rarechem Al Bo 0510; 2,4,5-Trifluorophenylaceticacid; 2,4,5-Trifluoro Phenyl Acetic acid; 2,4,5-Trifluorophenyl Acetic ACID; 2,4,5-FTA
Brief Introduction
2,4,5- three fluoro acetic acid is a white solid used to synthesize the intermediate of sitagliptin, a new drug for the treatment of type II diabetes. Sitagliptin is the first DPP-IV inhibitor of Merck company. It has good efficacy, side effects, safety and tolerance, and has broad market prospects.
CAS:241479-67-4
Molecular Formula:C22H17F2N5OS
4-[2-[(2R,3R)-3-(2,5-Difluorophenyl)-3-Hydroxy-4-(1,2,4-Triazol-1-yl)Butan-2-yl]-1,3-Thiazol-4-yl]Benzonitrile; 4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-Hydroxy-1-Methyl-3-(1H-1,2,4-Triazol-1-yl)Propyl]-4-Thiazolyl]Benzonitrile; Isavuconazole(BAL-4815)
Brief Introduction
Isaconazole is a novel extended spectrum triazole compound, which has activity against yeast, mold and dimorphic fungi and inhibits cytochrome P450 (CYP) - dependent 14 α- Lanosterol demethylation can inhibit the synthesis of ergosterol in fungal cell membrane. It is an antifungal drug.
CAS:33069-62-4
Molecular Formula:C47H51NO14
Taxol; Empac; Capxol; Onxal; Taxus; Taxol a; NK 105; DHP 107; ABI 007; Taxal; Paclitaxel HCL; Paclitaxel(Natural Crude); Paclitaxelx; N-Benzyl-Beta-Phenylisoserine Ester; Abraxane; Yewtaxan; Paxene; Genaxol; Paxceed; Paclitaxel (Natural)
Brief Introduction
Antineoplastic drugs. It is used to treat metastatic breast cancer and metastatic ovarian cancer. Broad-spectrum antineoplastic botanical drugs are used to treat ovarian cancer, breast cancer and other diseases.
CAS:330786-24-8
Molecular Formula:C17H13N5O
4-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazolo[3,4-d]Pyrimidine; Ibrutinib N-2; Ibrutinib Deacryloylpiperidine; 3-(4-Phenoxyphenyl)-2H-Pyrazolo[3,4-d]Pyrimidin-4-Amine; 5-(4-Phenoxyphenyl)-7H-Pyrrolo[2,3-d]Pyrimidin-4-Ylamine
Brief Introduction
Irutinib intermediate N-2 is a useful intermediate for the synthesis of irutinib; A highly selective irreversible inhibitor of Bruton tyrosine kinase (Btk).
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