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CAS:641571-10-0
Molecular Formula:C28H22F3N7O
Tasigna; Nilotinib (Amn-107); Its Intermediates; Nilotinib For Research; Nilotinib(Amn 107); Nilotinib,Amn107,Tasigna; Amn 107; Nilotinib D6
Brief Introduction
Nilotinib is a new targeted tumor therapeutic drug, which belongs to tyrosine kinase inhibitor. It is used to treat patients with chronic myeloid leukemia (CML) resistant to glipizide (imatinib). Gleevec is the preferred drug developed by Novartis for the treatment of chronic myeloid leukemia (CML). Nilotinib is improved from the molecular structure of imatinib. It has stronger selectivity for bcr-abl kinase activity. Its inhibitory effect on tyrosine kinase is 30 times stronger than imatinib. It can inhibit the kinase activity of BCR-ABL mutant resistant to imatinib. It can also inhibit kit and PDGFR kinase activities.
CAS:644-36-0
Molecular Formula:C9H10O2
O-Tolylacetic Acid; O-Methylphenylacetic Acid; 2-Methylphenyl Acetic Acid; 2-Tolylacetic Acid; O-Tolyacetic Acid; 2-Methylbenzeneacetic Acid
Brief Introduction
This product is mainly used as an intermediate in organic synthesis.
CAS:656247-18-6
Molecular Formula:C33H39N5O7S
3-Z-[1-(4-(N-((4-Methyl-Piperazin-1-Yl)-Methylcarbonyl)-N-Methyl-Amino)-Anilino)-1-Phenyl-Methylene]-6-Methoxycarbonyl-2-Indolinone Monoethanesulphonate; Ethanesulfonic Acid - Methyl (3Z)-3-{[(4-{Methyl[(4-Methyl-1-Pipe Razinyl)Acetyl]Amino}Phenyl)Amino](Phenyl)Methylene}-2-Oxo-6-Indo Linecarboxylate (1:1); Methyl (3Z)-3-[({4-[N-Methyl-2-(4-Methylpiperazin-1-Yl)Acetamido]Phenyl}Amino)(Phenyl)Methylidene]-2-Oxo-2,3-Dihydro-1H-Indole-6-Carboxylate Ethanesulfonate Salt; 3-Z-[1-(4-(N-((4-Methyl-Piperazin-1-Yl)-Methylcarbonyl)-N-Methyl-Amino)-Anilino)-1-Phenyl-Methylene]-6-Methoxycarbonyl-2-Indolinone Monoethanesulfonate Salt; (3S,5S)-3,5-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-1-Hydroxy-Cyclohexanecarboxylic Acid Methyl Ester
Brief Introduction
Nitanib ethylsulfonate is a small molecule inhibitor of multi receptor tyrosine kinase and non receptor tyrosine kinase. In 2014, it was approved by FDA for the first time, and was developed and sold by bringer Ingelheim company for the first time. It has been approved by the US Food and Drug Administration (FDA), the European Drug Administration (EMA) and the agency for drugs and medical devices (PMDA) for the treatment of idiopathic pulmonary fibrosis, and by EMA for non-small cell lung cancer.
CAS:65928-58-7
Molecular Formula:C20H25NO2
[14C]-Dienogest; 17A-Cyanomethyl-17B-Hydroxyestra-4,9-Dien-3-One; Dienogestril; Sts 557; [3H]-Dienogest; Endometrion; 17A-Cyanomethyl-17-Hydroxyestra-4,9-Dien-3-One; Dinagest; Dienogestrel; Dienogestum
Brief Introduction
Dinogestrin is a newly listed selective luteal hormone drug in recent years. It can play a role in stabilizing endometrial tissue by specifically binding ethylene nortestosterone and progesterone derivatives. It has been found that tumor necrosis factor (TNF). And interleukin-8 (IL-8) increased in patients with endometriosis.
CAS:66-22-8
Molecular Formula:C4H4N2O2
2,4-Dihydroxypyrimidine; 4-Hydroxy-2(1H)-Pyrimidinone; 4-Pyrimidinol; 4-Pyrimidone; 4H-Pyrimidin-2-one; Beta-Uracil; NSC 767; Uracil-4-ol; 2,4(1H,3H)-Pyrimidinedione; 2,4-Dioxo-3,4-Dihydropyrimidin; Urasil; 1H-Pyrimidine-2,4-Dione; 2,4-Pyrimidinediol
Brief Introduction
Uracil is an organic base, one of the four main bases in RNA, a major pyrimidine component in RNA, and also a component of various uridine acids. The triphosphate compound of uridine is urine triphosphate, which is the precursor of uracil in the process of ribonucleic acid biosynthesis. Urine triphosphate as coenzyme participates in the synthesis of some sugar biochemical books.
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