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CAS:42924-53-8
Molecular Formula:C15H16O2
Alias
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Mebutan; Relifen; Arthaxan; Relif; 4-(6-Methoxynaphthalen-2-Yl)Butan-2-One; Nabumetona; Relafen; Listran; Relifex; Dolsinal; 4-(6-Methoxy-2-Naphthyl)-2-Butanone
Brief Introduction
Nabumetone is a non-steroidal anti-inflammatory drug (NSAID), the only 1-naphthaleneacetic acid derivative. Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex, and Gambaran.
Nabumetone is a nonacidic NSAID that is rapidly metabolized in the liver to a major active metabolite, 6-methoxy-2-naphthyl acetic acid. As found with previous NSAIDs, nabumetone's active metabolite inhibits the cyclooxygenase enzyme and preferentially blocks COX-2 activity (which is indirectly responsible for the production of inflammation and pain during arthritis). The active metabolite of nabumetone is felt to be the compound primarily responsible for therapeutic effect. Comparatively, the parent drug is a poor inhibitor of COX-2 byproducts, particularly prostaglandins. It may be less nephrotoxic than indomethacin.
Nabumetone has little effect on renal prostaglandin secretion and less of an association with heart failure than other traditional drugs of the class. Effects of nabumetone on blood pressure control in hypertensive patients on ACE inhibitors is also good—equivalent to paracetamol. As of 2015 the cost for a typical month of medication in the United States is 25 to 50 USD.
CAS:4773-96-0
Molecular Formula:C19H18O11
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Hedysaride; Hedysarid; Mangifern; Aphloiol; Alpizarin; Chinonin; Chinomin; Alpizarine; Chinomine; Mangiferin Standard; 1,3,6,7-Tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)oxan-2-yl]Xanthen-9-one; 2-β-D-Glucopyranosyl-1,3,6,7-Tetrahydroxy-9H-Xanthen-9-one; 2-beta-d-Glucopyranosyl-1,3,6,7-Tetrahydroxy-9h-Xanthen-9-one
Brief Introduction
A natural phenolic flavonoid that has been investigated as an antimicrobial or antidiabetic drug with anti-inflammatory and antioxidant activity. Mangiferin can be used to help identify and characterize Type II 5-alpha-reductases. MGF can be used as a reference substance for flavonoid analysis. MGF may act as a promoter of gastrointestinal transit (GIT).
CAS:352303-67-4
Molecular Formula:C7H8BFO3
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Fluoro-3-Methoxyphenylboronic; 2-F,3-Meoc6H3B(Oh)2; 3-Borono-2-Fluoroanisole; 2-Fluoro-3-Methoxybenzeneboronic Acid; (2-Fluoro-3-Methoxyphenyl)Boronic acid
CAS:4295-55-0
Molecular Formula:C13H9Cl2NO2
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Clofenamic; Acidumclofenamic; 2-(2,3-Dichloroanilino)Benzoic Acid; 2-[(2,3-Dichlorophenyl)Amino]Benzoic Acid; N-2,3-Dichlorophenylanthranilic Acid; Benzoic Acid, 2-[(2,3-Dichlorophenyl)Amino]-
Brief Introduction
Used as an anti-inflammatory and analgesic.
CAS:5104-49-4
Molecular Formula:C15H13FO2
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1’-Biphenyl)-4-Aceticacid,2-Fluoro-Alpha-Methyl-(; 1’-Biphenyl]-4-Aceticacid,2-Fluoro-Alpha-Methyl-[; 2-(2-Fluoro-4-Biphenyl)Propionicacid; 2-(2-Fluoro-4-Biphenylyl)Propionicacid; 2-Fluoro-Alpha-Methyl-4-Biphenylaceticaci; (+/-)-Flurbiprofen; Ansaid; Froben; Stayban; fp70; 2-(2-Fluorobiphenyl-4-yl)Propionic Acid; Anside; Cebutid; Zepolas; Adfeed; Antadys
Brief Introduction
This product is an antipyretic analgesic. It is used for analgesia and anti-inflammatory of chronic arthritis and deformable arthritis, as well as analgesia after tooth extraction and surgery.
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