Hormones and Endocrine Drugs

Primobolan is a DEA Schedule III controlled substance. Substances in the DEA Schedule III have a potential for abuse less than substances in Schedules I or II and abuse may lead to moderate or low physical dependence or high psychological dependence.

Oxymetholone is an orally active synthetic anabolic steroid and a 17alpha-methylated derivative of dihydrotestosterone, with androgenic activity. Although oxymetholone has low affinity for binding the androgen receptor (AR), it strongly activates AR-mediated signaling, which stimulates both protein synthesis and erythropoietin production. This agent may stimulate muscle growth, induce hemoglobin production and red blood cell formation, and promote increased bone density.

Intermediate of prednisone acetate. It is an anti-inflammatory agent. It is used to treat adrenal hypofunction, rheumatoid arthritis, rheumatism, lupus erythematosus and other diseases.

Oxytocin, also known as oxytocin, is a uterine contractile drug, which can be extracted from the posterior pituitary of animals or chemically synthesized. The chemical synthetic product does not contain vasopressin, has no pressor effect, has selective excitation effect on uterine smooth muscle, and strengthens its contraction. The parturient uterus is the most sensitive to oxytocin (increased estrogen secretion), the immature uterus is not reactive to this product, and the uterus in the early or middle trimester of pregnancy has low reactivity to oxytocin, It gradually increased in the late pregnancy and reached the highest before labor. A small dose can strengthen the rhythmic contraction of the smooth muscle at the bottom of the uterus, strengthen its contractility, accelerate the contraction frequency, and maintain the polarity and symmetry similar to natural delivery. Therefore, it is clinically used for inducing labor. Large doses make the uterine muscles contract in a tetanic manner, which is clinically used to compress the blood vessels between muscle fibers, prevent postpartum hemorrhage and postpartum incomplete involution, and promote lactation, shrink the mammary duct, and promote the excretion of milk from the breast, but can not increase the secretion of milk, but can only promote the excretion of milk. It should be noted that the dosage and dropping speed should be strictly controlled when it is used to induce labor or labor, so as not to cause ankylosing uterine contraction, fetal asphyxia or uterine rupture. It is forbidden when there is cephalopelvic disproportion, fetal position or other birth canal abnormalities, uterine contraction is poor, there is a history of cesarean section and more than 3 times of maternity.

Fluhydrocortisone acetate is the only recommended mineralocorticoid drug for the treatment of salt deprived adrenal hyperplasia syndrome and Addison's syndrome in clinical guidelines in the United States. Fluhydrocortisone acetate mainly plays a role as a mineralocorticoid in primary adrenal insufficiency, and can be used together with glucocorticoids for replacement therapy. It is also suitable for low renin low aldosterone syndrome and orthostatic hypotension caused by autonomic neuropathy.