Bazedoxifene (TSE-424) is an oral active, non steroidal, selective estrogen receptor modulator (SERM) that can penetrate the blood-brain barrier α And ER β The IC50 values of action were 26 nm and 99 nm respectively, which can be used for the study of osteoporosis. Bazedoxifene is also an inhibitor of IL-6/GP130 protein interaction and can be used for pancreatic cancer research.

N-(4-Fluorophenyl)-4,5-Dimethyl-6-[(1S)-1-Methyl-3,4-Dihydro-1H-Isoquinolin-2-Yl]Pyrimidin-2-Amine

MSDS

CAS:199463-33-7

Molecular Formula:C22H23FN4

Alias

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Revaprazan [Inn]; N-(4-Fluorophenyl)-4,5-Dimethyl-6-(1-Methyl-3,4-Dihydro-1H-Isoquinolin-2-Yl)Pyrimidin-2-Amine; N-(4-Fluorophenyl)-4,5-Dimethyl-6-(1-Methyl-3,4-Dihydroisoquinolin-2(1H)-Yl)Pyrimidin-2-Amine

Brief Introduction

Revaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(nerd)).

Deferasirox

MSDS

CAS:201530-41-8

Molecular Formula:C21H15N3O4

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Exjade; Icl-670; Icl670A; 4-[3,5-Bis(2-Hydroxyphenyl)-1,2,4-Triazol-1-Yl]Benzoic Acid

Brief Introduction

1. DFS can be used to treat reversible renal insufficiency caused by Fanconi syndrome. 2. For the treatment of secondary hemochromatosis. 3. It can be used to treat delayed cutaneous porphyria. 4. For the treatment of myelodysplastic syndrome. 5. It is used to treat iron overload caused by blood transfusion in patients with chronic anemia aged 2 years and above.

2-Amino-N-(2,3-Dihydro-1H-Inden-2-Yl)Acetamide

MSDS

CAS:202844-10-8

Molecular Formula:C11H14N2O

Brief Introduction

Indantadol has been used in trials studying the treatment of Cough and Diabetic Peripheral Neuropathic Pain.

Clofazimine

MSDS

CAS:2030-63-9

Molecular Formula:C27H22Cl2N4

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Clofaziminum [Inn-Latin]; Clofaziminum; N,5-Bis(4-Chlorophenyl)-3-Propan-2-Yliminophenazin-2-Amine; Chlofazimine; Clofazimine (N,5-Bis(4-Chlorophenyl)-3,5-Dihydro-3-(Isopropylimino)Phenazin-2-Amine; Clofazimina [Inn-Spanish]; Lamprene; Lampren; 2-(4-Chloro-Anilino)-5-(4-Chloro-Phenyl)-3-Isopropylamino-Phenazinium-Betaine; 2-(4-Chlor-Anilino)-5-(4-Chlor-Phenyl)-3-Isopropylamino-Phenazinium-Betain; B 663 (Pharmaceutical); N,5-Bis(4-Chlorophenyl)-3,5-Dihydro-3-(Isopropylimino)Phenazin-2-Amine; Clofazimina

Brief Introduction

Clofazimine (nsc-141046) is a rhimophenazine dye, originally developed for the treatment of pulmonary tuberculosis, with antibacterial and anti-inflammatory activities. The mechanism of action includes the interaction between clofazimine and bacterial DNA to increase the level of intracellular phospholipase A2 (PLA2).

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