Pharmaceutical Raw Materials

Dauricine, also known as Dauricine, is a dibenzyltetrahydroisoquinoline alkaloid extracted and isolated from the rhizome of Dauricine (mountain bean root), a plant of tetrandriaceae. It is a toxic drug. Pharmacological studies show that Dauricine has antibacterial, antiarrhythmic, protective effect on myocardial ischemia, protective effect on cerebral ischemia and antitumor effects. The effect is similar to quinidine and has no anticholinergic effect. It can inhibit the transmembrane ion flow of potassium, sodium and calcium, reduce the maximum rising rate and amplitude of phase 0 of action potential, and prolong the time course of atrial and ventricular action potential. Reduce self-discipline and myocardial excitability, slow down heart rate and inhibit myocardial contractility. It has the characteristics of fast onset and slow recovery. Dauricine is a broad-spectrum antiarrhythmic drug with high curative effect and little side effects. It has been produced and applied in clinical practice. It is suitable for the treatment of tachyarrhythmia, especially for atrial, borderline and ventricular premature beats; It is also effective for preexcitation syndrome with ventricular tachycardia; It has poor effect on atrial flutter and fibrillation.

Pyridoxamine hydrochloride is a kind of vitamin medicine. Compound Sanwei B for injection is a compound preparation, which consists of furanthamine hydrochloride, pyridoxamine hydrochloride and vitamin B12. It is used to treat peripheral nerve injury, multiple neuritis, trigeminal neuralgia, pernicious anemia, nutritional anemia, etc. Pyridoxamine hydrochloride can be used as a pharmaceutical intermediate for the synthesis of other active compounds. For example, pyridoxamine hydrochloride is used as an intermediate to synthesize active molecules for the treatment of metabolic disorders.

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal (BD) and Diazolin (RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis. Mebhydrolin has been shown to enhance the performance-deficit effects of alcohol.

Medrylamine is an antihistamine related to diphenhydramine.

Flunarizine is an injection for the treatment of chronic vascular disease, peripheral vascular disease, central or peripheral vertigo, and has a good effect on chronic cold urticaria.