Methyldopa is a phenylalanine derivative and an aromatic amino acid decarboxylase inhibitor with antihypertensive activity. Methyldopa is a prodrug and is metabolized in the central nervous system. The antihypertensive action of methyldopa seems to be attributable to its conversion into alpha-methylnorepinephrine, which is a potent alpha-2 adrenergic agonist that binds to and stimulates potent central inhibitory alpha-2 adrenergic receptors. This results in a decrease in sympathetic outflow and decreased blood pressure.

N-Methyl-N-Propargylbenzylamine

MSDS

CAS:555-57-7

Molecular Formula:C11H13N

Alias

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N-Benzyl-N-Methylprop-2-Yn-1-Amine; Benzenemethanamine, N-Methyl-N-2-Propynyl-; Pargylamine; Pargyline; Paragyline

Brief Introduction

Pagarin is also called youjiangning. Pagarin is a monoamine oxidase inhibitor with obvious antihypertensive effect. The mechanism may be related to the inhibition of monoamine oxidase, resulting in abnormal tyramine metabolism in adrenergic nerve endings β- Related to hydroxytyramine. β- As a "pseudomediator", hydroxytyramine is stored and released instead of adrenaline, and binds with receptors to inhibit the conduction of postganglionic impulses, resulting in vasodilation and decreased blood pressure.

Ciclafrine

MSDS

CAS:55694-98-9

Molecular Formula:C15H21NO2

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Unii-76Hzx0Gvcd; Ciclafrina; Ciclafrinum; 3-(1-Oxa-4-Azaspiro[4.6]Undecan-2-Yl)Phenol

Brief Introduction

The molecular formula of 3-(1-oxa-4-azaspiro[4.6]undecan-2-yl)phenol is C15H21NO2.

1-Methoxypropane

MSDS

CAS:557-17-5

Molecular Formula:C4H10O

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Propane, 1-Methoxy-; Metopryl; Methyl Propyl Ether

Brief Introduction

Methyl propyl ether appears as a colorless volatile liquid with an ether-like odor. Less dense than water and insoluble in water. Vapors heavier than air. May be narcotic by inhalation in high concentrations. Used as a solvent and to make other chemicals.

1-(2-Cyclohexylphenoxy)-3-(Propan-2-Ylamino)Propan-2-Ol

MSDS

CAS:55837-19-9

Molecular Formula:C18H29NO2

Alias

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Exaprolol [Inn]; Exaprololum [Inn-Latin]; 1-(O-Cyklohexyl)Fenoxy-3-Izopropyl(Aminopropan-1-Ol) [Czech]; 1-Isopropylamino-3-(2-Cyclohexylphenoxy)-2-Propanol; Esaprololo [Dcit]; Exaprolol; 1-(2-Cyclohexylphenoxy)-3-((1-Methylethyl)Amino)-2-Propanol; Vulm 111; 2-Propanol,1-(2-Cyclohexylphenoxy)-3-((1-Methylethyl)Amino)

Brief Introduction

Exaprolol is a lipophilic derivative of the adrenergic blocking agent propranolol with sympatholytic activity. Exaprolol competitively binds to and blocks beta-adrenergic receptors in the heart and vascular smooth muscle, thereby causing negative chronotropic and inotropic effects leading to a reduction in cardiac output.

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