Organic Fluorine Compounds

Potassium Vinyltrifluoroborate is used as a catalyst in the synthesis of (+)-Varitriol, an antitumor natural product.

2,4,5-Trifluorobenzaldehyde is a reactant in the enantioselective synthesis of (R)-selegiline, an anti-Parkinson's drug, (S)-benzphetamine, an anti-obesity agent, and (S)-sitagliptin, an anti-diabetic drug.

1H,1H,2H,2H-perfluorooctanol acrylate is an organic fluoride, which can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Used as an intermediate for liquid crystal materials.

N-fluorobisbenzenesulfonamide is a new, stable and mild fluorination reagent. It can introduce fluorine atoms into the carbonyl ortho position of organic molecules and monofluorinate electron rich aromatic compounds, enol silicon ethers, enol lithium salts, etc. At present, the research focus is the five membered ring formation of Nazarov cyclization catalyzed by iron or cobalt α- Asymmetric catalysis of fluorination. This product is mainly used for palladium catalyzed enantioselective fluorination of TERT butoxycarbonyllactones and lactams. It can also be used for the electrophilic difluorination of dihalopyridines under the action of butyl lithium, and for the direct conversion of alcohols to diphenylsulfonimide compounds under the action of triphenylphosphine. Stable and easy to handle crystalline material, easy to transform f + into enol and negative carbon ions.