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Zhejiang Pure Pharmaceutical Co.,Ltd.

15 YRS

Zhejiang, China

CNY 76.9 Million

99900 m²

100-500 people

Main Products: Dexamethasone Sodium Phosphate / Abiraterone / Eplerenone / Hydroxyprogesterone / 21-Deacetoxy Deflazacort / Cortisol / Flumethasone / Fluticasone Propionate / Dehydroepiandrosterone

Zhejiang, China

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Hydroxyprogesterone / CAS 68-96-2

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

Max Capacity

120 MT/Year

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DESCRIPTION

17α-hydroxyprogesterone
CAS No	68-96-2	Molecular formula	C21H30O3
Molecular weight	330.461	Precision mass	330.219
LogP	3.6943	PSA	54.37

Indication:

1. Contraception for women of reproductive age.

2. Hydroxyprogesterone alone can treat habitual miscarriage, irregular menstruation, endometriosis and functional uterine bleeding and advanced breast cancer, among others.

Typical Properties

17α-Hydroxyprogesterone (17α-OHP), or hydroxyprogesterone (OHP) (INN, BAN), also known as 17α-hydroxypregn-4-ene-3,20-dione, is an endogenous progestogen steroid hormone related to progesterone. It is also a chemical intermediate in the biosynthesis of many other endogenous steroids, including androgens, estrogens, glucocorticoids, and mineralocorticoids, as well as neurosteroids. Under the brand name Gestageno, 17α-OHP has been marketed for clinical use in Argentina. However, esters of 17α-OHP, including hydroxyprogesterone caproate, as well as hydroxyprogesterone acetate and hydroxyprogesterone heptanoate to a much lesser extent, have been used far more widely in comparison, and when "hydroxyprogesterone" is referenced from the standpoint of medical use, what is usually being referred to is actually, in general, hydroxyprogesterone caproate. 17α-OHP is also the parent compound of a class of progestins referred to as the 17α-hydroxyprogesterone derivatives. Among others, this class of drugs includes chlormadinone acetate, cyproterone acetate, hydroxyprogesterone caproate, medroxyprogesterone acetate, and megestrol acetate.

CAS No.

68-96-2

Formula

C21H30O3

Molecular Mass

330.46100

Exact Mass

330.21900

PSA

54.37000

Logp

3.69430

IUPAC

(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

SMILES

CC(=O)C1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O

Matter Classification

organic

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