On Chemball
My Chemball
+86-571-8627 3270
Tipr Pharmaceutical Co.,Ltd.
Tipr Pharmaceutical Co.,Ltd.
30 YRS
Tianjin, China
Main Products:
Argatroban Monohydrate / Adefovir Dipivoxil / 1-Cyclohexyl-3-[4-[2-(7-Methoxy-4,4-Dimethyl-1,3-Dioxoisoquinolin-2-Yl)Ethyl]Phenyl]Sulfonylurea / Glipizide / Glyburide / Glimepiride / Candesartan Cilexetil / Aclatonium Napadisilate / Troxipide / Risperidone / Cucurbitacin B / Procaterol Hydrochloride Hemihydrate / Nimesulide
Tianjin, China
Send Email
Sending...
Thank You！
Your requirement has been sent, we will contact you quickly!
Sent Failed！
Try again!
Adefovir Dipivoxil / CAS 142340-99-6
OVERVIEW
Packaging
5 KG/Woven Bag
Lead Time
14-30 days
REQUEST A QUOTATION
SubmitGet Free Samples
Less than 1KG required
DESCRIPTION
Adefovir Dipivoxil
【Chemical Name】 9-[2-[Bis(pivaloyloxy) methoxy] phosphinyl]methoxy)ethyl]adenine
【CAS Number】142340-99-6
【Molecular Formula】C20H32N5O8P
【Molecular Weight】501.48
【Content】≥99.0%
【Therap-Cat】For treatment of chronic hepatitis B
【Package】5kg/bag
【Specification】SFDA
Typical Properties
Summary
Adefovir dipivoxil is an oral broad-spectrum antiviral drug, which was first synthesized by Gilead company of the United States. It was approved by FDA to be listed in the United States in September 2002. It is also another oral anti HBV drug after lamivudine. Adefovir dipivoxil is recommended as the first-line choice for newly diagnosed patients by the American Association for the study of liver diseases, the Asia Pacific Society for the study of liver and the Chinese guideline for the prevention and treatment of chronic hepatitis B. Adefovir dipivoxil can inhibit the activity of HBVDNA polymerase, and can penetrate into the DNA of hepatitis B virus, inhibit the replication of the virus, and have a strong inhibitory effect on lamivudine and pancyclovir resistant HBV virus, which is clinically used for the treatment of hepatitis.
CAS No.
142340-99-6
Formula
C20H32N5O8P
Molecular Mass
501.47100
Exact Mass
501.19900
PSA
176.79000
Logp
3.28370
IUPAC
[2-(6-aminopurin-9-yl)ethoxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate
SMILES
CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C(N=CN=C21)N)OCOC(=O)C(C)(C)C
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Immune System Medication
Chemical and Physical Properties
Melting Point
98-102ºC
Density
1.35 g/cm3
Boiling Point
641ºC
Appearance
White to off white crystalline powder
Export information
HS Code
29339900
Export Rebate
13%
Risk Code
R20/21/22
Safety Label
Xi，Xn
GET SAMPLE
Submit- Overview
- Descriptions
- Sample