On Chemball
My Chemball
+86-571-8627 3270
UPCHEM (CHINA) CO., LTD
UPCHEM (CHINA) CO., LTD
29 YRS
Zhejiang, China
Main Products:
Isocyanic Acid 3,4-Dichlorophenyl Ester / Bis(Trichloromethyl) Carbonate / Meta-Tolyl Isocyanate / 1-Isocyanato-4-Propan-2-Yl Benzene / 4-Tolyl Isocyanate / Tosyl Isocyanate / 2-Chlorobenzenesulfonyl Isocyanate / 1,5-Naphthalene Diisocyanate / 2-Chloro-2-Methylpropane
Zhejiang, China
Send Email
Sending...
Thank You！
Your requirement has been sent, we will contact you quickly!
Sent Failed！
Try again!
Tosyl Isocyanate / CAS 4083-64-1
OVERVIEW
Packaging
200 KG/Plastic Drum; 200 KG/Steel Drum
Lead Time
14-30 days
REQUEST A QUOTATION
SubmitGet Free Samples
Less than 1KG required
DESCRIPTION
P-Toluenesulfonyl isocyanate
Common name:p-Toluenesulfonyl isocyanate
Molecular formula: C8H7NO3S
Molecular weight: 197.21
CAS No: 4083-64-1
Physicochemical properties:
Colorless transparent liquid with low viscosity. Specific gravity: 1.29, viscosity:10mpa.s; boiling point: 270℃; freezing point: 5℃; flash point:＞100℃; hue:≤1
Quality index: content≥98.0%
Uses: pharmaceutical intermediate
Packing: 200 KG steel-plastic drum
Storage and transportation: shelf life is one year if the product is kept in original package under the condition of correct storage. To protect from light and heat.
Structural formula:
.jpg)
Typical Properties
Summary
This product is mainly used as an intermediate in the synthesis of medicine or pesticide, and can be used in the synthesis of doxazosin. Doxazosin is a α 1 selectivity α A blocker that inhibits norepinephrine from interacting with the membrane of vascular smooth muscle cells α- 1 receptor binding. The main effect of this inhibition is to relax the tension of vascular smooth muscle (vasodilation), which reduces peripheral vascular resistance and leads to lower blood pressure. * it is used clinically to treat hypertension and urinary retention associated with benign prostatic hyperplasia.
CAS No.
4083-64-1
Formula
C8H7NO3S
Molecular Mass
197.21100
Exact Mass
197.01500
PSA
71.95000
Logp
2.10030
IUPAC
4-methyl-N-(oxomethylidene)benzenesulfonamide
SMILES
CC1=CC=C(C=C1)S(=O)(=O)N=C=O
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Pharmaceutical Intermediates
Agrochemicals > Pesticide Intermediates
Agrochemicals > Pesticide Intermediates
Chemical and Physical Properties
Melting Point
5 °C
Density
1.291 g/mL
Boiling Point
144 °C（10 mm Hg）(lit.)
Flash Point
>230 °F
Appearance
Clear colorless to yellow liquid
Export information
HS Code
29291090
Export Rebate
13%
UN No.
2206
DG-Class
6.1
Risk Code
R14-36/37/38-42
Safety Label
Xn
GET SAMPLE
Submit- Overview
- Descriptions
- Sample