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Wuxi Taxus Pharmaceutical Co., Ltd.

Jiangsu, China

CNY 250 Million

39960 m²

100-500 people

Main Products: Paclitaxel / Allopurinol / Levomefolate Calcium / Docetaxel / Oxaliplatin / Irinotecan Hydrochloride / Praziquantel / Levomefolic Acid

Jiangsu, China

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Docetaxel / CAS 114977-28-5

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Docetaxel

English Name: Docetaxel

CAS No.: 114977-28-5

Molecular formula: C43H53NO14

Molecular weight: 807.88

EINECS No.: 601-339-2

Melting point: 186-192 ° C (Dec.)

Specific rotation: - 36 º (C = 0.74, EtOH)

Boiling point: 900.5 ± 65.0 ° C (predicted)

Density: 1.38

Uses: Docetaxel can be used to study antibiotics, cell biology, cell signal transduction, neuroscience, apoptosis and cell cycle. Docetaxel is also used to study hair loss caused by docetaxel chemotherapy, prevention and treatment of non-small cell lung cancer in patients with contraindicated standard chemotherapy. Docetaxel was also used to study hypoxia inducible factor-1 α And 2 α Role in androgen insensitive prostate cancer cells.

Typical Properties

Docetaxel is an anticancer and antitumor drug. It can be used to study antibiotics, cell biology, cell signal transduction, neuroscience, apoptosis and cell cycle. Docetaxel is also used to study hair loss caused by docetaxel chemotherapy, prevention and treatment of non-small cell lung cancer in patients with contraindicated standard chemotherapy.

CAS No.

114977-28-5

Formula

C43H53NO14

Molecular Mass

807.8790

Exact Mass

807.34700

PSA

224.45000

Logp

3.65050

IUPAC

[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

SMILES

CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Matter Classification

organic

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