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Wuxi Taxus Pharmaceutical Co., Ltd.

Jiangsu, China

CNY 250 Million

39960 m²

100-500 people

Main Products: Paclitaxel / Allopurinol / Levomefolate Calcium / Docetaxel / Oxaliplatin / Irinotecan Hydrochloride / Praziquantel / Levomefolic Acid

Jiangsu, China

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Oxaliplatin / CAS 61825-94-3

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Oxaliplatin

English Name: oxaliplatin

CAS No.: 61825-94-3

Molecular formula: C8H12N2O4Pt

Molecular weight: 395.28

EINECS No.: 621-248-1

Overview:Oxaliplatin is a platinum derivative. Clinically, it is used to treat patients with colorectal cancer metastasis after fluorouracil treatment failure. It can be used alone or in combination with fluorouracil. It is the third generation of new platinum antitumor compounds after cisplatin and carboplatin. It is also the only platinum drug with significant activity for colorectal cancer. The principle of action is to produce alkylation conjugates to act on DNA, form intra chain and inter chain crosslinks, and inhibit DNA synthesis and replication. It also inhibits the proliferation of ovarian cancer and melanoma cell lines

Uses: antitumor drugs for the treatment of rectal cancer

Typical Properties

Oxaliplatin, which belongs to platinum derivatives and is clinically used to treat patients with colorectal cancer metastases after failure of fluorouracil treatment, either alone or in combination with fluorouracil, is the third-generation novel platinum based antitumor compound after cisplatin, carboplatin and the only complex platinum based drug with significant activity against colorectal cancer to date. The principle of action is to act on DNA by producing alkylated conjugates, forming intra - and interstrand crosslinks that inhibit DNA synthesis and replication. It also inhibited proliferation in ovarian cancer and melanoma cell lines.

CAS No.

61825-94-3

Formula

C8H14N2O4Pt

Molecular Mass

397.28600

Exact Mass

397.06000

PSA

104.64000

Logp

0.61450

IUPAC

[(1R,2R)-2-azanidylcyclohexyl]azanide;oxalic acid;platinum(2+)

SMILES

C1CCC(C(C1)[NH-])[NH-].C(=O)(C(=O)O)O.[Pt+2]

Matter Classification

organic

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