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Zhejiang Dongsheng New Material Technology Co.,Ltd.

29 YRS

Anhui, China

CNY 10 Million

133200 m²

Less than 50 people

Main Products: 4,6-Dichloro-5-(2-Methoxyphenoxy)-2,2'-Bipyrimidine / N-{6-Chloro-5-(2-Methoxy Phenoxy)[2,2'-Bipyrimidin]-4-yl}-4-(1,1-Dimethylethyl) Benzensulfonamide / 5-(2-Methoxyphenoxy)-[2,2'-Bipyrimidine]-4,6(1H,5H)-Dione / 2-Cyanopyrimidine / 2-Chloropyrimidine / Pyrimidine-2 Carboxamidine HCl / Linezolid / 3-Fluoro-4-Morpholinoaniline / (S)-5-(Aminomethyl)-3-(3-Fluoro-4-Morpholinophenyl)Oxazolidin-2-one / (5R)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-5-Hydroxymethyl-2-Oxazolidione / R-[3-(3-Fluoro-(4-Morpholinophenyl)-2-oxo-5-Oxazolidinyl]Methyl Methznsulfonarte / (5R)-5-(Chloromethyl)-3-[3-Fluoro-4-(4-Morpholinyl)Phenyl]-2-Oxazolidione / Cefozopran Hydrochloride / 2-(5-Amino-1,2,4-Thiadiazol-3-Yl)-2-Methoxyimino Acetic Acid / 6-Chloroimidazo[1,2b]-Pyridazine / Imidazo[1,2-b]Pyridazine / 3-Amino-6-Chloropyridazine

Anhui, China

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2-Cyanopyrimidine / CAS 14080-23-0

OVERVIEW

Uses

Bosentan Bosentan

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

2-Cyanopyrimidine

Product Name: 2-Cyanopyrimidine

CAS NO：14080-23-0

Molecular formula: C5H3N3

Molecular weight: 105.09

Appearance: white to yellow powder

Application: pharmaceutical intermediate, bosentan intermediate

Typical Properties

2-Cyanopyrimidine is a key intermediate in the synthesis of bosentan. Bosentan is a kind of drug for the treatment of pulmonary hypertension, which is suitable for the treatment of patients with pulmonary hypertension (PAH) of who functional classification II-IV (who group 1), in order to improve the exercise ability of patients and reduce clinical deterioration. Studies supporting the effectiveness of this product mainly included patients with idiopathic or hereditary PAH (60%) of who functional classification II-IV, PAH associated with connective tissue disease (21%) and PAH associated with left to right shunt congenital heart disease (18%).

CAS No.

14080-23-0

Formula

C5H3N3

Molecular Mass

105.09700

Exact Mass

105.03300

PSA

49.57000

Logp

0.34828

IUPAC

pyrimidine-2-carbonitrile

SMILES

C1=CN=C(N=C1)C#N

Matter Classification

organic

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