On Chemball
My Chemball
+86-571-8627 3270
Zhongtao New Materials Co., Ltd.
Zhongtao New Materials Co., Ltd.
10 YRS
Ningxia, China
Main Products:
L-1-Phenylethylamine / (1R)-1-Phenylethanamine / Adamantane / 1-Bromoadamantane / Amantadine / 1-Adamantanamine Hydrochloride
Ningxia, China
Send Email
Sending...
Thank You！
Your requirement has been sent, we will contact you quickly!
Sent Failed！
Try again!
1-Adamantanamine hydrochloride intermediate / CAS 665-66-7
REQUEST A QUOTATION
SubmitGet Free Samples
Less than 1KG required
DESCRIPTION
1-Adamantanamine hydrochloride intermediate
Name：1-Adamantanamine hydrochloride intermediate | Chinese Name：盐酸金刚烷胺中间体 |
CASNO.：665-66-7 | Molecular weight：187.71 |
Molecular formula：C10H18ClN | Appearance: White crystalline powder |
Structure type： | |
Typical Properties
Summary
Amantadine Hydrochloride is the hydrochloride salt of amantadine, a synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect against the influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the release of infectious viral nucleic acids into host cells; furthermore, this agent prevents virus assembly during virus replication. Amantadine exerts its antiparkinsonian effects by stimulating the release of dopamine from striatal dopaminergic nerve terminals and inhibiting its pre-synaptic reuptake. This agent may also exert some anticholinergic effect through inhibition of N-methyl-D-aspartic acid (NMDA) receptor-mediated stimulation of acetylcholine, resulting in antihyperalgesia.
CAS No.
665-66-7
Formula
C10H18ClN
Molecular Mass
187.71000
Exact Mass
187.11300
PSA
26.02000
Logp
3.41620
IUPAC
adamantan-1-amine;hydrochloride
SMILES
C1C2CC3CC1CC(C2)(C3)N.Cl
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Nervous System Drugs
Chemical and Physical Properties
Melting Point
>300 °C
Density
1.067g/cm3
Boiling Point
225.7ºC
Flash Point
96ºC
Appearance
White crystalline powder.
Export information
HS Code
29213000
Export Rebate
13%
Risk Code
R22-40-20/21/22
Safety Label
Xn
GET SAMPLE
Submit- Overview
- Descriptions
- Sample
