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Shanghai Bocimed Pharmaceutical Co.,Ltd.
Shanghai Bocimed Pharmaceutical Co.,Ltd.
12 YRS
Shanghai, China
Main Products:
Relugolix / Carfilzomib / Ixazomib Citrate / Apalutamide / Avatrombopag / Fulvestrant / Lenvatinib Mesylate / Ruxolitinib Phosphate / Roxadustat / Brivaracetam
Shanghai, China
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Carfilzomib / CAS 868540-17-4
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Carfilzomib
CAS:868540-17-4
Molecular formula: C40H57N5O7
Molecular weight: 719.91000
Appearance: White powder
Introduction: Carfilzomib is the second proteasome inhibitor approved worldwide after bortezomib, and the first multiple myeloma treatment drug approved by the FDA in recent years (proteasome inhibitor: protease The main role of the body is to degrade unwanted or damaged proteins in cells, which is achieved by chemical reactions that break peptide bonds). Carfilzomib is a new-generation protease inhibitor administered intravenously that selectively targets the proteasome in hematological tumor cells, avoiding the toxic side effects of inhibiting the constitutive proteasome in non-malignant cells.
Structural formula:
Typical Properties
Summary
Carfilzomib is a proteasome inhibitor. Proteasome can decompose proteins that are damaged or no longer needed, thus playing an important role in cell function and growth.
CAS No.
868540-17-4
Formula
C40H57N5O7
Molecular Mass
719.91000
Exact Mass
719.42600
PSA
158.47000
Logp
4.08500
IUPAC
(2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide
SMILES
CC(C)CC(C(=O)C1(CO1)C)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Immune System Medication
API & Intermediate > Inhibitors
API & Intermediate > Inhibitors
Chemical and Physical Properties
Density
1.162g/cm3
Boiling Point
975.627ºC at 760 mmHg
Flash Point
543.84ºC
Appearance
White powder
Export information
HS Code
29349990
Export Rebate
10%
UN No.
0.0
DG-Class
0.0
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