On Chemball
My Chemball
+86-571-8627 3270
Suzhou Lixin Pharmaceutical co.,ltd
Suzhou Lixin Pharmaceutical co.,ltd
24 YRS
Jiangsu, China
Main Products:
Pemetrexed Acid / Oxaliplatin / Clopidogrel Bisulfate / Viread / Imatinib Mesylate / Capecitabine / Temozolomide / Nilotinib Hydrochloride Monohydrate
Jiangsu, China
Send Email
Sending...
Thank You！
Your requirement has been sent, we will contact you quickly!
Sent Failed！
Try again!
Temozolomide / CAS 85622-93-1
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
REQUEST A QUOTATION
SubmitGet Free Samples
Less than 1KG required
DESCRIPTION
Temozolomide
CAS:85622-93-1
Molecular formula：C6H6N6O2
Molecular weight：194.15100
Appearance:White or whitish crystalline powder
Synopsis: Temozolomide is the first oral effective imidazo tetrazine antitumor drug. It belongs to the second generation alkylating agent with antitumor activity. It does not need intrahepatic metabolic activation after oral administration. It is characterized by easy penetration through the blood-brain barrier, good tolerance and no superimposed toxicity with other drugs. It has synergistic effect with radiotherapy. It is suitable for malignant gliomas that relapse after routine treatment, For example, glioblastoma multiforme or degenerative astrocytoma is also the first-line drug for the treatment of metastatic melanoma.
Structural formula:
Typical Properties
Summary
Temozolomide is the first oral effective imidazo tetrazine antitumor drug. It belongs to the second generation alkylating agent with antitumor activity. It does not need intrahepatic metabolic activation after oral administration. It is characterized by easy penetration through the blood-brain barrier, good tolerance and no superimposed toxicity with other drugs. It has synergistic effect with radiotherapy. It is suitable for malignant gliomas that relapse after routine treatment, For example, glioblastoma multiforme or degenerative astrocytoma is also the first-line drug for the treatment of metastatic melanoma.
CAS No.
85622-93-1
Formula
C6H6N6O2
Molecular Mass
194.15100
Exact Mass
194.05500
PSA
108.17000
Logp
-1.37780
IUPAC
3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
SMILES
CN1C(=O)N2C=NC(=C2N=N1)C(=O)N
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Antineoplastic Agents
Chemical and Physical Properties
Melting Point
212°C dec.
Density
1.97 g/cm3
Boiling Point
526.6ºC at 760 mmHg
Flash Point
272.3ºC
Appearance
white solid
Export information
HS Code
2933990099
Export Rebate
13%
UN No.
0.0
DG-Class
0.0
Risk Code
R45
Safety Label
T; Xi
GET SAMPLE
Submit- Overview
- Descriptions
- Sample
