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Suzhou Lixin Pharmaceutical co.,ltd
Suzhou Lixin Pharmaceutical co.,ltd
24 YRS
Jiangsu, China
Main Products:
Pemetrexed Acid / Oxaliplatin / Clopidogrel Bisulfate / Viread / Imatinib Mesylate / Capecitabine / Temozolomide / Nilotinib Hydrochloride Monohydrate
Jiangsu, China
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Oxaliplatin / CAS 61825-94-3
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Oxaliplatin
CAS:61825-94-3
Molecular formula：C8H14N2O4Pt
Molecular weight：397.28600
Appearance:White or whitish crystalline powder
Synopsis: Oxaliplatin, which belongs to platinum derivatives and is clinically used to treat patients with colorectal cancer metastases after failure of fluorouracil treatment, either alone or in combination with fluorouracil, is the third-generation novel platinum based antitumor compound after cisplatin, carboplatin and the only complex platinum based drug with significant activity against colorectal cancer to date. The principle of action is to act on DNA by producing alkylated conjugates, forming intra - and interstrand crosslinks that inhibit DNA synthesis and replication. It also inhibited proliferation in ovarian cancer and melanoma cell lines.
Structural formula:
Typical Properties
Summary
Oxaliplatin, which belongs to platinum derivatives and is clinically used to treat patients with colorectal cancer metastases after failure of fluorouracil treatment, either alone or in combination with fluorouracil, is the third-generation novel platinum based antitumor compound after cisplatin, carboplatin and the only complex platinum based drug with significant activity against colorectal cancer to date. The principle of action is to act on DNA by producing alkylated conjugates, forming intra - and interstrand crosslinks that inhibit DNA synthesis and replication. It also inhibited proliferation in ovarian cancer and melanoma cell lines.
CAS No.
61825-94-3
Formula
C8H14N2O4Pt
Molecular Mass
397.28600
Exact Mass
397.06000
PSA
104.64000
Logp
0.61450
IUPAC
[(1R,2R)-2-azanidylcyclohexyl]azanide;oxalic acid;platinum(2+)
SMILES
C1CCC(C(C1)[NH-])[NH-].C(=O)(C(=O)O)O.[Pt+2]
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Antineoplastic Agents
Chemical and Physical Properties
Boiling Point
193.6ºC at 760 mmHg
Flash Point
75ºC
Appearance
White or whitish crystalline powder
Export information
HS Code
71101100
Export Rebate
0%
Export Formalities
8,x
Risk Code
/37/38-40-42/43
Safety Label
Xn,Xi
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