Basic Information of 2-Pyridinethanol / CAS 103-74-2
- English Name: 2-(2-Hydroxyethyl)pyridine or 2-Hydroxyethyl Pyridine or 2-Pyridinethanol
- CAS Number: 103-74-2
- Molecular Formula: C7H9NO
- Molecular Weight: 123.15
- Appearance: Colorless to slightly yellow transparent liquid, miscible with ethanol, ether, and water, hygroscopic
- Physical Properties: Boiling point around 114-116°C (at lower pressure), density 1.093 g/mL (at 25°C), flash point 92.78°C, refractive index 1.5368-1.537
Chemical Properties
- Due to the presence of hydroxyl and pyridine rings, 2-(2-Hydroxyethyl)pyridine exhibits certain hydrophilicity and reactivity.
- It can participate in various organic synthesis reactions, such as catalytic reactions and free-radical polymerization reactions.
Specifications of 2-Pyridinethanol / CAS 103-74-2
Item | Standard Requirements |
Grade | Top Grade | Qualified Grade |
Properties | Colorless to pale yellow liquid |
Purity (GC) | ≥99.0% | ≥98.0% |
Moisture | ≤0.2% | ≤0.2% |
Production Method of 2-Pyridinethanol / CAS 103-74-2
- 2-(2-Hydroxyethyl)pyridine can be synthesized through the addition reaction of 2-methylpyridine and formaldehyde. Under nitrogen protection, the mixture of formaldehyde and 2-methylpyridine is heated to a certain temperature, and then subjected to reduced pressure distillation to collect the specific fraction.
Primary Uses of 2-Pyridinethanol / CAS 103-74-2
- Pharmaceutical Intermediate: As a key intermediate in drug synthesis, 2-Hydroxyethyl Pyridine is used to synthesize various biologically active drugs, such as antibiotics, antiviral drugs, and anticancer drugs.
- Flame Retardant: With certain flame retardant properties, it can be used in the production of flame retardants for polymers and plastics, enhancing the fire resistance of materials.
- Polymer Materials: In polymerization reactions, 2-Hydroxyethyl Pyridine serves as a chain transfer agent, regulating the molecular weight and molecular weight distribution of polymers, thereby affecting their properties and structures.
- Electronic Materials: It can be a component of organic semiconductor materials, used in the preparation of electronic devices such as organic thin-film transistors (OFETs).
- Other Applications: It is also applied in the pharmaceutical industry, engineering plastics, ion exchange resins, and chemical films.
Safety Precautions of 2-Pyridinethanol / CAS 103-74-2
- When working with 2-(2-Hydroxyethyl)pyridine, follow laboratory safety procedures, wear appropriate protective equipment, and ensure adequate ventilation.
- Avoid direct skin contact and inhalation of its vapors. In case of accidental contact, rinse immediately with water and seek medical attention.
- Storage: 2-(2-Hydroxyethyl)Pyridine should be stored in a dry, ventilated, and cool warehouse. If the storage time is long, a polymerization inhibitor should be added, and attention should be paid to fire prevention. It is strictly prohibited to store it together with flammable materials and oxidants. This product has a shelf life of 6 months from the date of production.
- Transportation: During the transportation of this product, please pay attention to sealing, keeping it cool, and preventing leakage.
Fuyang Xinyihua Pharmaceutical Technology Co.,Ltd. was established in May 2017 with a registered capital of 228.5 million yuan. The company is located in Taihe County Economic Development Zone, Fuyang City, the largest western medicine distribution center in China and a provincial-level chemical concentration zone. Mainly engaged in the research and development, production, and sales of specialty pharmaceutical intermediates and active pharmaceutical ingredients, while providing professional pharmaceutical CMO/CDMO services. The current phase of the factory has a pilot workshop, two large multifunctional production workshops, and multiple standardized production lines, which can meet different process conditions such as -100 ℃~200 ℃ and 200Pa~7MPa.
With high-quality technology and manufacturing capabilities, the company has established stable customer relationships with hundreds of well-known domestic pharmaceutical companies, accumulated over 60 potential projects, and applied for more than 40 patents.
Keywords Related to 2-Pyridinethanol / CAS 103-74-2
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