On Chemball

My Chemball

As Supplier

My RFQ Manage Products

As Buyer

My RFQ Post RFQ

My Account

+86-571-8627 3270

Joyang Laboratories

17 YRS

Jiangsu, China

CNY 201.0 Million

113220 m²

100-500 people

Main Products: Bacitracin Zinc / Bacitracin / Fusidic Acid / Fusidate Sodium / Cyclosporin A / Mycophenolate Mofetil / Mycophenolic Acid / Pioglitazone Hydrochloride / Capecitabine / Febuxostat

Jiangsu, China

Contact Supplier

Home Company Profile Contact Us Post Buying Request

Bacitracin / CAS 1405-87-4

OVERVIEW

Packaging

10 KG/Fibre Drum

Lead Time

14-30 days

REQUEST A QUOTATION

Submit

Get Free Samples

Less than 1KG required

DESCRIPTION

Bacitracin

1、Nomenclature

English name:Bacitracin

2、Structural formula

Molecular

Structure

杆菌肽

Molecular formula of Bacitracin A：C66H103N17O16S

Molecular weight of Bacitracin A：1422.69

CAS号CAS No.：1405-87-4

3、Mechanism and clinical use:

Bacitracin is used in medicine as a polypeptide antibiotic. Bacitracin has bactericidal action for Gram-positive bacteria & Gram-negative coccobacteria, diplococcus lanceolatus, staphylococcus, gonococcus, diplococcus intracellularis, leptospiral, etc. The mechanism of action: act on cell wall and effect protoplast, damage cellular plasma membrane and effect permeability.

It is mainly used for infection of penicillin-resistant staphylococcus, also used for skin infection, etc. Under specific concentration, it has relatively strong bactericidal action for systemic infection and topical infection. Its antibacterial spectrum is similar to penicillin G. It is often used by combination with polymyxin, neomycin.

4、Packaging size specification

Inner package: single-layer polyethylene bag and aluminum foil bag.

Outer package: fiber drum.

Packaging size: 10 Kg/drum

Typical Properties

The product is mainly used as an animal growth promoter in feed. Due to the presence of zinc, cadmium and mercury salts, the activity of the product is enhanced, so the zinc and manganese salts of the product are often used as feed additives. Growth promoters are non nutritive additives, which can stimulate the growth of livestock and poultry, improve the rate of weight gain and feed utilization, and improve the health of livestock and poultry. It has strong antibacterial activity against most Gram-positive bacteria, similar to penicillin, and also effective against penicillin resistant Staphylococcus aureus. As a drug, it is mainly used to treat various infections caused by drug-resistant staphylococcus aureus, such as sepsis, pneumonia, endocarditis, etc.

CAS No.

1405-87-4

Formula

C66H103N17O16S

Molecular Mass

1422.69

Exact Mass

1421.75

PSA

556.17000

Logp

3.72410

IUPAC

(4S)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2R,3S)-1-[[(3R,6R,9R,12R,15R,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid

SMILES

CC[C@H](C)[C@@H]1C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N[C@@H](C(=O)NCCCC[C@@H](C(=O)N[C@@H](C(=O)N1)CCCN)NC(=O)[C@@H]([C@@H](C)CC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CSC(=N2)[C@H]([C@@H](C)CC)N)CC(=O)N)CC(=O)O)CC3=CN=CN3)CC4=CC=CC=C4

GET SAMPLE