On Chemball

My Chemball

As Supplier

My RFQ Manage Products

As Buyer

My RFQ Post RFQ

My Account

+86-571-8627 3270

Zhejiang Bulk Chemical Co.,Ltd.

21 YRS

Zhejiang, China

CNY 39 Million

14652 m²

Less than 50 people

Main Products: N,N-Dimethylformamide Dimethyl Acetal / Sopropyl Isothiocyanate / Ethyl Isothiocyanate / 1-Phenyltetrazole-5-Thiol / 1-Hydroxybenzotriazole / 1,3-Diisopropylcarbodiimide

Zhejiang, China

Contact Supplier

Home Company Profile Contact Us Post Buying Request

N-Hydroxybenzotriazole / CAS 2592-95-2

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

REQUEST A QUOTATION

Submit

Get Free Samples

Less than 1KG required

DESCRIPTION

N-Hydroxybenzotriazole

CAS：2592-95-2

Molecular formula：C6H5N3O

Molecular weight：135.12

Product introduction:

Hydroxybenzotriazole (HOBt), white crystal, 1n hydroxy substituted derivative of benzotriazole. It is often used as racemization inhibitor in peptide synthesis. When using DCC dehydration condensation to prepare peptides, the chiral center of the substrate can not be well maintained in the product due to the high activity of DCC. Generally, additives such as hydroxybenzotriazole are added to reduce the activity of activated ester and inhibit racemization.

Product purpose:

Synthesis of intermediate and polypeptide protective agent of ubenimex. Used as an intermediate in organic synthesis.

Typical Properties

Hydroxybenzotriazole (HOBt), white crystal, 1n hydroxyl substituted derivative of benzotriazole. It is often used as racemization inhibitor in peptide synthesis. When DCC dehydration condensation is used to prepare peptides in the classical method, the chiral center of the substrate can not be well maintained in the product due to the high activity of DCC. Generally, additives such as hydroxybenzotriazole are added to reduce the activity of activated esters to inhibit racemization. See details See peptide synthesis. Hydroxybenzotriazole is usually sold as monohydrate crystal (~ 11.7% water, weight). Anhydrous hydroxybenzotriazole is explosive and should be paid attention to when used.

CAS No.

2592-95-2

Formula

C6H5N3O

Molecular Mass

135.12300

Exact Mass

135.04300

PSA

61.80000

Logp

0.66350

IUPAC

1-hydroxybenzotriazole

SMILES

C1=CC=C2C(=C1)N=NN2O

Matter Classification

organic

GET SAMPLE