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Kaifeng Mingren Pharmaceutical Co.,LTD.
Kaifeng Mingren Pharmaceutical Co.,LTD.
22 YRS
Henan, China
Main Products:
Phloroglucinol Anhydrous / Phlorglucinol Dihydrate / Vidarabine Monophosphate / Creatine Phosphate Disodium Salt / 2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]Pyrimidine / Guanfacine Hydrochloride###Guanfacine Hcl / Fomepizole / Nitisinone / Epalrestat / Nafamostat Mesylate / Doxofylline / (S)-3-Cyano-5-Methylhexanoic Acid Ethyl Ester / 4-(6-Fluoropyridin-3-yl)-6-(2-Hydroxy-2-Methylpropoxy)Pyrazolo[1,5-a]Pyridine-3-Carbonitrile / Methyl 5-((4-Bromo-2-Chlorophenyl)Amino)-4-Fluoro-1-Methyl-1H-Benzo[d]Imidazole-6-Carboxylate / Benzyl (3R,4S)-3-(2-Bromoacetyl)-4-Ethylpyrrolidine-1-Carboxylate / 5-Bromo-4,7-Diazaindole / (2R,3R)-3-(2,5-Difluorophenyl)-3-Hydroxy-2-Methyl-4-(1H-1,2,4-Triazol-1-yl)Butanethioamide / 4-(2-Bromoacetyl)Benzonitrile / Isavuconazole
Henan, China
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Phloroglucinol anhydrous
Phlorglucinol Dihydrate
Vidarabine Monophosphate
Creatine Phosphate Disodium Salt
2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]Pyrimidine
Guanfacine Hydrochloride###Guanfacine Hcl
Fomepizole
Nitisinone
Epalrestat
Nafamostat Mesylate
Doxofylline
(S)-3-Cyano-5-Methylhexanoic Acid Ethyl Ester
4-(6-Fluoropyridin-3-yl)-6-(2-Hydroxy-2-Methylpropoxy)Pyrazolo[1,5-a]Pyridine-3-Carbonitrile
Methyl 5-((4-Bromo-2-Chlorophenyl)Amino)-4-Fluoro-1-Methyl-1H-Benzo[d]Imidazole-6-Carboxylate
Benzyl (3R,4S)-3-(2-Bromoacetyl)-4-Ethylpyrrolidine-1-Carboxylate
5-Bromo-4,7-Diazaindole
(2R,3R)-3-(2,5-Difluorophenyl)-3-Hydroxy-2-Methyl-4-(1H-1,2,4-Triazol-1-yl)Butanethioamide
4-(2-Bromoacetyl)Benzonitrile
Isavuconazole
Isavuconazole / CAS 241479-67-4
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Chemical name
English name： Isavuconazole
CAS No.: 241479-67-4
Physicochemical properties：
Molecular formula: C22H17F2N5OS
Structural type: 
Molecular weight: 437.465
Boiling point: 678ºC at 760 mmHg
Density： 1.38 g/cm³
Character: White to off white solid crystalline powder
Purpose: Isaconazole is a novel extended spectrum triazole compound, which has activity against yeast, mold and dimorphic fungi and inhibits cytochrome P450 (CYP) - dependent 14 α- Lanosterol demethylation can inhibit the synthesis of ergosterol in fungal cell membrane. It is an antifungal drug.
Typical Properties
Summary
Isaconazole is a novel extended spectrum triazole compound, which has activity against yeast, mold and dimorphic fungi and inhibits cytochrome P450 (CYP) - dependent 14 α- Lanosterol demethylation can inhibit the synthesis of ergosterol in fungal cell membrane. It is an antifungal drug.
CAS No.
241479-67-4
Formula
C22H17F2N5OS
Molecular Mass
437.46500
Exact Mass
437.11200
PSA
115.86000
Logp
4.24298
IUPAC
4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile
SMILES
CC(C1=NC(=CS1)C2=CC=C(C=C2)C#N)C(CN3C=NC=N3)(C4=C(C=CC(=C4)F)F)O
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Other Chemical Drugs
Chemical and Physical Properties
Density
1.38
Boiling Point
678ºC at 760 mmHg
Flash Point
363.8ºC
Appearance
White to off white solid crystalline powder
Export information
HS Code
29332900
Export Rebate
13%
UN No.
0.0
DG-Class
0.0
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