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Weightech (Hunan) Pharmaceutical Co., Ltd.
Weightech (Hunan) Pharmaceutical Co., Ltd.
21 YRS
Hunan, China
Main Products:
Telmisartan / Irbesartan / Olmesartan Medoxomi / Pantoprazole Sodium / Tildenafil
Hunan, China
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Telmisartan / CAS 144701-48-4
OVERVIEW
Packaging
15 KG/Fibre Drum
Lead Time
14-30 days
Max Capacity
11 MT/Year
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DESCRIPTION
Telmisartan
Product name | Telmisartan |
CAS | 144701-48-4 |
Molecular formula | C33H30N4O2 |
Molecular mass | 514.62 |
Structural formula |
|
Appearance | White to off-white crystalline powder |
Purity | 99% |
Certification | GMP |
Raw material grade | Pharmaceutical grade |
Storage | Sealed storage |
Packaging | Packed in double medical polyethylene bag, 15 kg/barrel |
Typical Properties
Summary
Telmisartan is a new type of antihypertensive drug, which is a specific angiotensin II receptor antagonist for the treatment of essential hypertension. The substitution of angiotensin Ⅱ receptor for at Ⅰ receptor subtype has high affinity binding. Telmisartan has no agonist effect at the at I receptor site, but selectively binds to at I receptor, which is persistent. It has no affinity for other receptors. The function of other receptors mentioned above is unknown, and the possible receptor hyperstimulation effect caused by telmisartan is also unknown. Telmisartan did not inhibit plasma renin or block ion channels. It did not inhibit angiotensin converting enzyme II, which could also degrade bradykinin induced adverse reactions.
CAS No.
144701-48-4
Formula
C33H30N4O2
Molecular Mass
514.61700
Exact Mass
514.23700
PSA
72.94000
Logp
7.26440
IUPAC
2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
SMILES
CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C=C(C=C2C)C5=NC6=CC=CC=C6N5C
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Circulatory System Drugs
Chemical and Physical Properties
Melting Point
261-263 °C
Density
1.16 g/cm3
Boiling Point
771.9 ºC
Flash Point
420.6 ºC
Appearance
White or grayish white crystalline powder
Acidity and Basicity
alkalinity acidness
Export information
HS Code
29339900
Export Rebate
13%
Risk Code
R36/37/38
Safety Label
Xi
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