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Weightech (Hunan) Pharmaceutical Co., Ltd.
Weightech (Hunan) Pharmaceutical Co., Ltd.
21 YRS
Hunan, China
Main Products:
Telmisartan / Irbesartan / Olmesartan Medoxomi / Pantoprazole Sodium / Tildenafil
Hunan, China
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Irbesartan / CAS 138402-11-6
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
Max Capacity
1 MT/Year
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DESCRIPTION
Irbesartan
Product name | Irbesartan |
CAS | 138402-11-6 |
Molecular formula | C25H28N6O |
Molecular mass | 428.53 |
Structural formula |
|
Appearance | White or off-white powder |
Purity | 99% |
Certification | GMP |
Raw material grade | Pharmaceutical grade |
Storage | Sealed storage |
Packaging | Packed in double medical polyethylene bag, 25 kg/barrel |
Typical Properties
Summary
Irbesartan is an angiotensin II receptor inhibitor, which can be divided into AT1 and AT2. Irbesartan can inhibit the transformation of Ang Ⅰ into ang Ⅱ by selectively blocking the AT1 receptor of ANGLI, and specifically antagonize the angiotensin converting enzyme 1 receptor. The antagonism of irbesartan to AT1 is 8500 times that of AT2, It can inhibit the vasoconstriction and the release of aldosterone. This product does not inhibit angiotensin converting enzyme, renin, other hormone receptors, and ion channels related to blood pressure regulation and sodium balance. Irbesartan is the most effective drug in the treatment of hypertension and cardiovascular disease.
CAS No.
138402-11-6
Formula
C25H28N6O
Molecular Mass
428.52900
Exact Mass
428.23200
PSA
87.13000
Logp
4.15090
IUPAC
2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
SMILES
CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Circulatory System Drugs
Chemical and Physical Properties
Melting Point
180-181°C
Density
1.3 g/cm3
Boiling Point
648.6ºC
Flash Point
346ºC
Appearance
White crystalline powder
Acidity and Basicity
acidness alkalinity
Export information
HS Code
29339900
Export Rebate
13%
UN No.
3276
DG-Class
6.1
Risk Code
R22
Safety Label
Xn
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