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English Name: Imatinib
CAS No.: 152459-95-5
Molecular formula: C29H31N7O
Molecular weight: 493.6
EINECS No.: 604-855-6
Product Description: imatinib is an oral drug used to treat adult patients with Philadelphia chromosome (BER ABL) - positive chronic myeloid leukemia (CML) in the acute phase, accelerated phase and chronic phase after interferon treatment failure. CML is a hematopoietic stem cell disease caused by abnormal DNA of stem cells in bone marrow. Abnormal DNA will produce abnormal proteins, interfere with the normal production of leukocytes in bone marrow, and eventually lead to a sharp increase in the number of leukocytes. CML is divided into three stages: chronic stage, accelerated stage and crisis stage. The average survival time of patients in crisis stage is only 2-3 months. Imatinib is also effective in the treatment of gastrointestinal stromal tumors, with an effective rate of about 50%.
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