Synopsis：Letitrexed is a quinazoline folate analogue. Its antitumor effect is produced by specific inhibition of thymidine synthase. In the treatment of colorectal cancer, its curative effect is similar to that of fluorouracil, but it has less toxic and side effects than fluorouracil, and the administration method is relatively simple.
Structural formula:
Properties
Summary
Letitrexed is a quinazoline folate analogue. Its antitumor effect is produced by specific inhibition of thymidine synthase. In the treatment of colorectal cancer, its curative effect is similar to that of fluorouracil, but it has less toxic and side effects than fluorouracil, and the administration method is relatively simple.
Manufacturing
